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颅内动脉瘤性蛛网膜下腔出血的流行病学。

Epidemiology of aneurysmal subarachnoid hemorrhage.

机构信息

Department of Neurological Surgery, Columbia University Medical Center, 630 West 168th Street, P&S Building 5-454, New York, NY 10032, USA.

出版信息

Neurosurg Clin N Am. 2010 Apr;21(2):221-33. doi: 10.1016/j.nec.2009.10.002.

DOI:10.1016/j.nec.2009.10.002
PMID:20380965
Abstract

Aneurysmal subarachnoid hemorrhage (aSAH) is a form of hemorrhagic stroke that affects up to 30,000 individuals per year in the United States. The incidence of aSAH has been shown to be associated with numerous nonmodifiable (age, gender, ethnicity, family history, aneurysm location, size) and modifiable (hypertension, body mass index, tobacco and illicit drug use) risk factors. Although early repair of ruptured aneurysms and aggressive postoperative management has improved overall outcomes, it remains a devastating disease, with mortality approaching 50% and less than 60% of survivors returning to functional independence. As treatment modalities change and the percentage of minority and elderly populations increase, it is critical to maintain an up-to-date understanding of the epidemiology of SAH.

摘要

颅内动脉瘤性蛛网膜下腔出血(aSAH)是一种出血性脑卒中,在美国每年影响多达 30000 人。aSAH 的发病率与许多不可改变的(年龄、性别、种族、家族史、动脉瘤位置、大小)和可改变的(高血压、体重指数、烟草和非法药物使用)危险因素有关。尽管早期修复破裂的动脉瘤和积极的术后管理改善了整体预后,但它仍然是一种毁灭性的疾病,死亡率接近 50%,不到 60%的幸存者恢复到功能独立性。随着治疗方式的改变和少数族裔和老年人口比例的增加,及时了解蛛网膜下腔出血的流行病学至关重要。

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