Department of Kinesiology, Iowa State University, Ames, IA 50011, USA.
Arch Phys Med Rehabil. 2010 Apr;91(4):632-8. doi: 10.1016/j.apmr.2009.12.016.
To determine if gait stability, as measured by harmonic ratios (HRs) derived from trunk accelerations, is improved during 3 amplitude-based cueing strategies (visual cues, lines on the floor 20% longer than preferred step length; verbal cues, experimenter saying "big step" every third; cognitive cues, participants think "big step") in people with Parkinson's disease.
Gait analysis with a triaxial accelerometer.
University research laboratory.
A volunteer sample of persons with Parkinson's disease (N=7) (Hoehn and Yahr stages 2-3).
Not applicable
Gait stability was quantified by anterior-posterior (AP), vertical, and mediolateral (ML) HRs; higher ratios indicated improved gait stability. Spatiotemporal parameters assessed were walking speed, stride length, cadence, and the coefficient of variation for stride time.
Of the amplitude-based cues, verbal and cognitive resulted in the largest improvements in the AP HR (P=.018) with a trend in the vertical HR as well as the largest improvements in both stride length and velocity. None of the cues positively affected stability in the ML direction. Descriptively, all participants increased speed and stride length, but only those in Hoehn and Yahr stage 2 (not Hoehn and Yahr stage 3) showed improvements in HRs.
Cueing for "big steps" is effective for improving gait stability in the AP direction with modest improvements in the vertical direction, but it is not effective in the ML direction. These data support the use of trunk acceleration measures in assessing the efficacy of common therapeutic interventions.
通过测量源自躯干加速度的谐和比（HRs），确定在 3 种基于振幅的提示策略（视觉提示、比预期步长长 20%的地板线；口头提示、实验者每走三步说一次“大步”；认知提示、参与者想着“大步”）下，帕金森病患者的步态稳定性是否得到改善。
使用三轴加速度计进行步态分析。
大学研究实验室。
帕金森病患者的志愿者样本（N=7）（Hoehn 和 Yahr 分期 2-3）。
不适用。
采用前-后（AP）、垂直和横-侧向（ML）HRs 来量化步态稳定性；更高的比值表明步态稳定性得到改善。评估的时空参数包括步行速度、步长、步频和步时变异性系数。
在基于振幅的提示中，口头和认知提示导致 AP HR 最大改善（P=.018），垂直 HR 也有改善趋势，以及步长和速度的最大改善。没有提示对 ML 方向的稳定性产生积极影响。描述性地，所有参与者都提高了速度和步长，但只有 Hoehn 和 Yahr 分期 2（而非 Hoehn 和 Yahr 分期 3）的参与者 HRs 有所改善。
提示“大步”可以有效地改善 AP 方向的步态稳定性，对垂直方向有适度改善，但对 ML 方向无效。这些数据支持使用躯干加速度测量来评估常见治疗干预的效果。
