Department of Mechanical Engineering, University of Victoria, Victoria, BC, CanadaV8W 3P6.
Lab Chip. 2010 Jul 7;10(13):1732-4. doi: 10.1039/c002754e. Epub 2010 Apr 12.
A microfluidic reactor strategy for reducing plug-to-plug transport in gas-liquid segmented flow microfluidic reactors is presented. The segmented flow is generated in a wetting portion of the chip that transitions downstream to a partially wetting reaction channel that serves to disconnect the liquid plugs. The resulting residence time distributions show little dependence on channel length, and over 60% narrowing in residence time distribution as compared to an otherwise similar reactor. This partial wetting strategy mitigates a central limitation (plug-to-plug dispersion) while preserving the many attractive features of gas-liquid segmented flow reactors.
提出了一种用于减少气液分段流动微流控反应器中塞子到塞子传输的微流控反应器策略。分段流动在芯片的润湿部分产生,然后向下游过渡到部分润湿的反应通道,该通道用于断开液体塞。所得的停留时间分布几乎不依赖于通道长度,与其他类似的反应器相比,停留时间分布的宽度缩小了 60%以上。这种部分润湿策略缓解了一个主要限制(塞子到塞子的分散),同时保留了气液分段流动反应器的许多吸引人的特点。