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儿童腹腔结核病。

Abdominal tuberculosis in children.

机构信息

Department of Pediatrics B, Children's Hospital of Tunis, Tunis, Tunisia.

出版信息

J Pediatr Gastroenterol Nutr. 2010 Jun;50(6):634-8. doi: 10.1097/MPG.0b013e3181b6a57b.

Abstract

BACKGROUND

Abdominal tuberculosis (TB) includes infection of the gastrointestinal tract, peritoneum, mesentery, abdominal lymph nodes, liver, spleen, and pancreas. The most common forms of abdominal TB in children are adhesive peritonitis and nodal disease.

PATIENTS AND METHODS

We report our experience with abdominal TB treated in our hospital from 1995 to 2008.

RESULTS

Thirteen patients (3 boys and 10 girls) of mean age 9.8 years were diagnosed as having abdominal TB. Eight patients presented with abdominal distension and abdominal pain. Fever was seen in 4 patients. One patient had surgical abdominal pain and 2 had abdominal mass. Two patients had coexisting pleural effusion and 1 of them had multifocal TB. Abdominal TB involved peritoneum in 9, abdominal lymph nodes in 7, gastrointestinal tract in 3, spleen in 2 patients, and liver in 1. Ascitic fluid analysis of 9 patients showed exudative fluid with predominately lymphocytes. Laparotomy was performed in 3 patients. The diagnosis of abdominal TB was confirmed histopathologically in 5 patients and microbiologically in 3. The remaining patients had been diagnosed by ascitic fluid diagnostic features, abdominal imaging, tuberculin skin test, history of exposure, and a positive response to antituberculous treatment. Twelve patients completed the antituberculous therapy without any complications. One patient with multifocal TB had neurological sequelae.

CONCLUSIONS

In the areas with a high prevalence of tuberculosis and confirmatory investigations are inadequately available, treatment may be initiated, based on strong clinical diagnosis and supportive investigations. In such situations, it is the response to therapy that indirectly proves the diagnosis.

摘要

背景

腹部结核(TB)包括胃肠道、腹膜、肠系膜、腹部淋巴结、肝、脾和胰腺感染。儿童腹部 TB 最常见的形式是粘连性腹膜炎和淋巴结病。

患者和方法

我们报告了我们在 1995 年至 2008 年期间在我院治疗的腹部 TB 经验。

结果

13 名患者(3 名男孩和 10 名女孩)的平均年龄为 9.8 岁,被诊断为腹部 TB。8 名患者出现腹部膨隆和腹痛。4 名患者发热。1 名患者有手术性腹痛,2 名患者有腹部肿块。2 名患者同时伴有胸腔积液,其中 1 名患者有多灶性 TB。9 例腹部 TB 累及腹膜,7 例累及腹部淋巴结,3 例累及胃肠道,2 例累及脾脏,1 例累及肝脏。9 例患者的腹水分析显示渗出液以淋巴细胞为主。3 例行剖腹手术。5 例患者的诊断通过组织病理学证实,3 例患者通过微生物学证实。其余患者通过腹水诊断特征、腹部影像学、结核菌素皮肤试验、接触史和对抗结核治疗的阳性反应进行诊断。12 名患者完成了抗结核治疗,没有任何并发症。1 名有多灶性 TB 的患者有神经后遗症。

结论

在结核病高发地区,如果没有足够的确诊性检查,可根据强烈的临床诊断和支持性检查开始治疗。在这种情况下,间接证明诊断的是治疗反应。

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