Hair Science Institute, Amsterdam, The Netherlands.
J Dermatolog Treat. 2010 Nov;21(6):337-49. doi: 10.3109/09546630903359814.
There are different stem cell pools located in the hair follicle.
To try to determine whether follicular units can survive a partial extraction and whether this partial extracted follicular unit can regenerate new hairs.
From five individuals, between 100 and 150 grafts were harvested from the occipital area of the scalp. Suitable grafts were implanted into the recipient area. Hair growth and characteristics in the donor area and the recipient area were observed at different intervals.
After 3 months, between 92.1% and 104.1% (mean 97.7%) of the partial follicular units in the donor sites survived and produced hairs with the same characteristics. After 1 year, 91.1–101.7% (mean 95.9%) of the implanted partial follicular units regenerated hair growth with the same characteristics as the hairs in the donor area.
We revealed that extracted partial longitudinal follicular units transplanted to the recipient area can be used as complete follicular units to regenerate completely differentiated hair growth with the same characteristics as in the donor area. We also revealed that the partial follicular units in the donor area can survive and produce the same number of hairs with the same characteristics. This technique enables us to generate two hair follicles from one follicle with consistent results and preserve the donor area.
毛囊中存在不同的干细胞池。
尝试确定毛囊单位是否能在部分提取后存活，以及这种部分提取的毛囊单位是否能再生新的毛发。
从五名个体的头皮枕部采集了 100 到 150 个移植体。合适的移植体被植入受区。观察供区和受区的毛发生长和特征在不同的时间间隔。
3 个月后，供区部分毛囊单位中有 92.1%到 104.1%（平均 97.7%）存活，并产生了具有相同特征的毛发。1 年后，91.1%到 101.7%（平均 95.9%）的植入部分毛囊单位再生出与供区毛发相同特征的毛发生长。
我们揭示了提取的部分纵向毛囊单位移植到受区后可以作为完整的毛囊单位，再生出与供区相同特征的完全分化的毛发生长。我们还揭示了供区的部分毛囊单位可以存活并产生相同数量和特征的毛发。这项技术使我们能够从一个毛囊中产生两个具有一致结果的毛囊，并保留供区。
