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头皮毛囊的形态计量学分析:对毛发移植医师和毛发再生研究的实际意义。

Morphometric analysis of the human scalp hair follicle: practical implications for the hair transplant surgeon and hair regeneration studies.

机构信息

Clínica Dr. Jiménez Acosta, Las Palmas de Gran Canaria, Spain.

出版信息

Dermatol Surg. 2011 Jan;37(1):58-64. doi: 10.1111/j.1524-4725.2010.01809.x. Epub 2010 Nov 11.

DOI:10.1111/j.1524-4725.2010.01809.x
PMID:21070465
Abstract

BACKGROUND

The bulge stem cell region is a structure important for the regeneration of the pilosebaceous unit. Measurements of the different compartments of a hair follicle may have implications in hair transplantation and hair regeneration studies.

OBJECTIVE

To measure the length of the different portions of the occipital scalp hair and to estimate at what depth they are located.

METHODS AND MATERIAL

Hair follicles from the occipital scalp were obtained from 29 individuals. Measurements were performed on digital pictures using a software imaging system. Antibody anticytokeratin (CK), 15 was used as a bulge stem cell marker.

RESULTS

The mean length of a scalp hair follicle is 4.16 mm. The infundibulum measures 0.76 mm, the isthmus 0.89 mm, and the inferior portion 2.5 mm. The insertion of the arrector pili muscle is located 1.65 mm deep. CK15 immunoreactivity starts at a depth of 1 mm and extends down to 1.8 mm.

CONCLUSION

The ideal depth for the trichophytic procedure is to cut the wound edge at a depth of less than 1 mm to avoid the bulge zone. The data provided can serve as an objective anatomical reference in hair regeneration studies using horizontally transected follicles.

摘要

背景

隆突干细胞区域是毛球单位再生的重要结构。毛囊不同部位的测量可能对毛发移植和毛发再生研究有影响。

目的

测量枕部头皮头发的不同部位的长度,并估计它们位于多深的位置。

方法和材料

从 29 个人的枕部头皮获得毛囊。使用软件成像系统对数字图片进行测量。抗体抗细胞角蛋白(CK)15 被用作隆突干细胞标志物。

结果

头皮毛囊的平均长度为 4.16 毫米。漏斗部为 0.76 毫米,峡部为 0.89 毫米,下部为 2.5 毫米。竖毛肌的插入位于 1.65 毫米深。CK15 免疫反应从 1 毫米深开始,延伸至 1.8 毫米深。

结论

对于毛发移植程序,理想的深度是将切口边缘切割到小于 1 毫米的深度,以避免隆突区。提供的数据可作为使用水平切割毛囊的毛发再生研究的客观解剖参考。

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