University of Leipzig, Germany.
Int J Psychiatry Med. 2009;39(4):345-58. doi: 10.2190/PM.39.4.a.
Depression is very common in people above 65 years living in long-term care. However, little is known about how well depression is recognized and how adequately it is treated. Therefore, the present study aimed at assessing accuracy of the unaided clinical diagnosis of the attending physicians, and the medical treatment situation in nursing home residents.
A random sample of 97 residents of 10 nursing homes in Munich was examined with the Section A "Affective Syndrome" of the Structured Clinical Interview (SCID) for DSM-IV to detect depression. Information concerning clinical diagnosis and medication was obtained from the subjects' medical records.
14.4% suffered acutely from major depression, 14.4% suffered from minor depression, and 18.6% were diagnosed as depressive according to the physician and nursing records. In total, 27.8% received antidepressants. Merely 42.9% of the subjects with acute major depression were diagnosed by their attending physicians as depressive, and only half of them received an antidepressant; 17.5% received antidepressants without a diagnosis of depression in their physician and nursing records. In accordance with the guidelines, 73.3% of the antidepressants prescribed were SSRIs or newer antidepressants. Only 20.0% were tricyclic antidepressants.
Findings show that depression is relatively frequent in residents of nursing homes. Moreover, it is insufficiently recognized by physicians and is even more seldom adequately treated. Also, a significant proportion of residents receive antidepressants without a documented associated indication. Therefore, the recognition and guideline-based treatment of depression should be improved in this high-risk group.
在长期护理机构中,65 岁以上的人群中抑郁症非常常见。然而,对于抑郁症的识别程度以及治疗的充分程度知之甚少。因此,本研究旨在评估主治医生的非辅助临床诊断的准确性,以及疗养院居民的医疗治疗情况。
从慕尼黑的 10 家养老院中随机抽取了 97 名居民,使用 DSM-IV 结构化临床访谈(SCID)的 A 节“情感综合征”对他们进行检查,以检测抑郁症。从患者的病历中获取有关临床诊断和用药的信息。
14.4%的人患有急性重度抑郁症,14.4%的人患有轻度抑郁症,根据医生和护理记录诊断为抑郁的有 18.6%。总共,27.8%的人接受了抗抑郁药治疗。仅有 42.9%的急性重度抑郁症患者被主治医生诊断为抑郁,只有一半的人接受了抗抑郁药治疗;17.5%的人在医生和护理记录中未被诊断出抑郁症却接受了抗抑郁药治疗。根据指南,开具的抗抑郁药中 73.3%为 SSRIs 或新型抗抑郁药。仅 20.0%为三环类抗抑郁药。
研究结果表明,疗养院居民中抑郁症较为常见。此外,医生对其识别不足,治疗也更不充分。此外,相当一部分居民接受抗抑郁药治疗而没有明确的相关适应症。因此,应该改善这一高风险群体中抑郁症的识别和基于指南的治疗。