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恶性骨质石化症:骨髓移植后的高钙血症

Malignant osteopetrosis: hypercalcaemia after bone marrow transplantation.

作者信息

Rawlinson P S, Green R H, Coggins A M, Boyle I T, Gibson B E

机构信息

Department of Haematology, Royal Infirmary, Glasgow.

出版信息

Arch Dis Child. 1991 May;66(5):638-9. doi: 10.1136/adc.66.5.638.

Abstract

A 3 year old girl presented with malignant osteopetrosis, which was treated by allogeneic bone marrow transplantation. Successful engraftment was complicated by prolonged hypercalcaemia, which was controlled by a combination of a bisphosphonate, phosphate infusions, vigorous resalination, and salmon calcitonin. She was alive and well 16 months after the transplant.

摘要

一名3岁女童患有恶性骨质石化症,接受了异基因骨髓移植治疗。成功植入后出现了持续的高钙血症并发症,通过双膦酸盐、磷酸盐输注、积极补液和鲑鱼降钙素联合治疗得以控制。移植后16个月,她存活且状况良好。

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