Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Gothenburg SE-416 85, Sweden.
Hum Reprod. 2010 Jun;25(6):1415-22. doi: 10.1093/humrep/deq095. Epub 2010 Apr 14.
There is a need to improve our understanding of contraceptive use over the long term. The aims of this study were to describe contraceptive use and pregnancies in the same women followed prospectively from 19 to 44 years of age.
In 1981, a postal questionnaire about contraception, pregnancies and reproductive health was sent to a random sample (n = 656) of 19-year-old women resident in Gothenburg, Sweden. The responders were contacted again every fifth year.
At 19 years of age, 74% of the women had already used contraception and this increased to 98% at 44 years. Combined oral contraception was the commonest method currently used up to 29 years of age (48/51/22% at 19/24/29 years of age, respectively) and thereafter an intrauterine device (IUD: 34/39/38% at 34/39/44 years of age, respectively). Condom use alone during the 25-year study period was: 14/12/24/21/21/15% and non-use of contraception was: 35/24/26/20/21/26%. The mean number of pregnancies/children increased from 0.2/0.1 at 19 years of age to 3.1/2.1 at 44 years. Women who had been pregnant and women who had not been pregnant <or=19 years of age were compared up to 44 years of age (months of OC use: 69/107, P < 0.01; months of IUD use: 126/91, P < 0.01; 4.2/2.9 pregnancies, P < 0.001; 2.5/2.1 children, P< 0.09).
Choice of contraception was strongly related to age and parity, and the cumulative total number of pregnancies at 44 years of age, and contraceptive choice was related to age at first pregnancy.
我们需要增进对长期使用避孕措施的了解。本研究旨在描述在相同的女性中使用避孕措施和怀孕的情况,并对其进行前瞻性研究,随访时间为 19 岁至 44 岁。
1981 年,我们向瑞典哥德堡随机抽取的 656 名 19 岁女性寄出了一份关于避孕、怀孕和生殖健康的邮寄调查问卷。每隔五年我们会联系这些应答者一次。
19 岁时,74%的女性已经使用过避孕措施,到 44 岁时,这一比例上升至 98%。在 29 岁之前,最常用的避孕方法是复方口服避孕药(分别为 48/51/22%,在 19/24/29 岁时),之后是宫内节育器(IUD:分别为 34/39/38%,在 34/39/44 岁时)。在 25 年的研究期间,单独使用避孕套的比例为:14/12/24/21/21/15%,未使用避孕措施的比例为:35/24/26/20/21/26%。怀孕次数/孩子数从 19 岁时的 0.2/0.1 增加到 44 岁时的 3.1/2.1。比较了怀孕过和 19 岁前未怀孕的女性在 44 岁时的情况(使用口服避孕药的月数:69/107,P<0.01;使用宫内节育器的月数:126/91,P<0.01;怀孕次数:4.2/2.9,P<0.001;孩子数:2.5/2.1,P<0.09)。
避孕措施的选择与年龄和生育次数密切相关,44 岁时的累积怀孕次数,以及避孕措施的选择与首次怀孕年龄相关。