Can Mehmet M, Tanboğa Ibrahim H, Ozveren Olcay, Karabay Can Yucel, Akgün Taylan, Türkyilmaz Erdem, Tokgöz Hacer C, Kaymaz Cihangir, Serebruany Victor
Department of Cardiology, Kartal Koşuyolu Institute, Istanbul, Turkey.
Cardiology. 2010;115(4):307-10. doi: 10.1159/000312749. Epub 2010 Apr 16.
Narrowing of the iliac artery is a common presentation of systemic atherosclerosis. With the recent development of invasive techniques, angioplasty and stenting offer excellent results for fixing limb ischemia of aorto-iliac arteries. However, despite novel interventional approaches and constantly increasing experience, complications such as distal embolization, stent migration, acute or subacute iliac artery occlusion, dissection, and perforations are still challenging. Early restenosis and/or reocclusion of peripheral artery stents is uncommon, but the risk of delayed or late thrombotic occlusions of iliac artery stents is unclear. Although with questionable impact, hypercoagulable state or patient noncompliance may contribute to the pathogenesis of stent thrombosis. We describe a patient with terminal renal cell carcinoma who developed late iliac artery stent thrombosis despite dual chronic antiplatelet therapy with aspirin and clopidogrel.
髂动脉狭窄是全身性动脉粥样硬化的常见表现。随着近年来介入技术的发展,血管成形术和支架置入术在治疗主-髂动脉肢体缺血方面取得了优异的效果。然而,尽管有新颖的介入方法且经验不断增加,但诸如远端栓塞、支架移位、急性或亚急性髂动脉闭塞、夹层形成和穿孔等并发症仍然具有挑战性。外周动脉支架早期再狭窄和/或再闭塞并不常见,但髂动脉支架延迟或晚期血栓形成闭塞的风险尚不清楚。尽管影响存疑,但高凝状态或患者依从性差可能促成支架血栓形成的发病机制。我们描述了一名终末期肾细胞癌患者,尽管接受了阿司匹林和氯吡格雷双重慢性抗血小板治疗,但仍发生了晚期髂动脉支架血栓形成。