Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada.
Ann Surg. 2010 May;251(5):952-8. doi: 10.1097/SLA.0b013e3181d97589.
To develop a method of evaluating trauma center mortality that addresses the limitations of currently available methodology-Standardized Mortality Ratios (SMRs) based on the Trauma and Injury Severity Score.
TRISS SMRs have important limitations including inadequate risk adjustment, comparison to an inappropriate standard, lack of consideration for inter- and intrahospital variation, and incomparability across hospitals.
The methodology was developed using data from a provincial trauma registry with mandatory participation of all trauma centers, uniform inclusion criteria, and standardized data collection methods. Institutional performance was described with estimates of risk-adjusted mortality derived from a hierarchical logistic regression model. Risk adjustment was performed with a risk score generated by the Trauma Risk Adjustment Model (TRAM), as well as a term for incoming transfers and an interaction between transfer and the risk score. Outliers were identified by comparing each hospital to all remaining hospitals.
The study population comprised 88,235 patients including 4731 deaths (5.4%) from 59 trauma centers. Crude mortality varied between 1.3% and 14.3%. TRAM-adjusted mortality estimates varied between 3.7% (95% CI: 3.2%-4.3%) and 6.9% (5.8%-8.2%). Three trauma centers had significantly higher adjusted mortality and one center had statistically significant lower mortality when compared with all other centers.
The proposed method of trauma center profiling offers comprehensive adjustment for patient-level risk factors and consideration of transfer status, is based on comparisons to an internal standard, accounts for inter- and intrahospital variation, and replaces SMRs with estimates of regression-adjusted mortality that are comparable across hospitals. TRAM-adjusted mortality estimates can be used to describe institutional outcome performance and to identify institutional outliers. Such information is the key to identifying ways to improve the quality of modern trauma care.
开发一种评估创伤中心死亡率的方法,该方法解决了当前基于创伤和损伤严重程度评分的标准化死亡率比(SMR)方法的局限性。
TRISS SMR 存在重要的局限性,包括风险调整不足、与不适当的标准进行比较、缺乏对医院内和医院间差异的考虑以及医院之间的不可比性。
该方法使用来自省级创伤登记处的数据开发,该登记处要求所有创伤中心强制性参与,具有统一的纳入标准和标准化的数据收集方法。通过来自层次逻辑回归模型的风险调整死亡率估计来描述机构绩效。风险调整使用创伤风险调整模型(TRAM)生成的风险评分、传入转移项以及转移与风险评分之间的交互作用来完成。通过将每个医院与所有其他医院进行比较来识别离群值。
研究人群包括 88235 名患者,其中 59 个创伤中心有 4731 例死亡(5.4%)。死亡率为 1.3%-14.3%。TRAM 调整后的死亡率估计值在 3.7%(95%CI:3.2%-4.3%)至 6.9%(5.8%-8.2%)之间变化。与所有其他中心相比,有 3 个创伤中心的调整后死亡率明显较高,有 1 个中心的死亡率明显较低。
提出的创伤中心分析方法为患者水平的风险因素提供了全面的调整,并考虑了转移状态,基于与内部标准的比较,考虑了医院内和医院间的差异,并使用可在医院之间比较的回归调整后死亡率估计值代替 SMR。TRAM 调整后的死亡率估计值可用于描述机构结果绩效,并识别机构离群值。此类信息是识别提高现代创伤护理质量方法的关键。