Stein Quinn P, Flanagan Jason D
Sanford Women's Health & Sanford Children's Specialty Clinic, South Dakota, USA.
S D Med. 2010;Spec No:16-22.
Knowledge of cancer genetics is advancing our biological understanding of breast, colon, prostate and lung cancers. A family history of any one of these four types of cancer can increase an individual's personal risk to also develop a malignancy. For some families, genetic testing, in combination with genetic counseling, can be a helpful way to identify a hereditary cancer predisposition gene or establish a cancer risk management plan. In this paper, we will review the current state of knowledge surrounding genetic factors influencing breast, colon, prostate and lung cancer.
癌症遗传学知识正在增进我们对乳腺癌、结肠癌、前列腺癌和肺癌的生物学理解。这四种癌症中任何一种的家族病史都会增加个体患恶性肿瘤的个人风险。对于一些家庭来说，基因检测与遗传咨询相结合，可能是识别遗传性癌症易感基因或制定癌症风险管理计划的有用方法。在本文中，我们将综述有关影响乳腺癌、结肠癌、前列腺癌和肺癌的遗传因素的当前知识状况。
