• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Inherited susceptibility to common cancers.

作者信息

Foulkes William D

机构信息

Program in Cancer Genetics, Department of Oncology, McGill University, Montreal, QC, Canada.

出版信息

N Engl J Med. 2008 Nov 13;359(20):2143-53. doi: 10.1056/NEJMra0802968.

DOI:10.1056/NEJMra0802968
PMID:19005198
Abstract
摘要

相似文献

1
Inherited susceptibility to common cancers.常见癌症的遗传易感性。
N Engl J Med. 2008 Nov 13;359(20):2143-53. doi: 10.1056/NEJMra0802968.
2
Genetic and familial factors influencing breast, colon, prostate and lung cancers.影响乳腺癌、结肠癌、前列腺癌和肺癌的遗传及家族因素。
S D Med. 2010;Spec No:16-22.
3
Hereditary cancer predisposition syndromes.遗传性癌症易感性综合征。
J Clin Oncol. 2005 Jan 10;23(2):276-92. doi: 10.1200/JCO.2005.10.042.
4
Why have we failed to find the low penetrance genetic constituents of common cancers?为什么我们未能找到常见癌症的低外显率遗传成分?
Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1544-9.
5
[Genetic susceptibility to lung and head and neck cancers].[肺癌及头颈部癌的遗传易感性]
Pathol Biol (Paris). 2010 Dec;58(6):e87-9. doi: 10.1016/j.patbio.2008.11.002. Epub 2009 Feb 6.
6
Inherited predisposition to cancer: a historical overview.癌症的遗传易感性:历史概述。
Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):5-22. doi: 10.1002/ajmg.c.30026.
7
ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes.美国临床肿瘤学会/外科肿瘤学会对降低风险手术在常见遗传性癌症综合征中的当前作用的综述。
J Clin Oncol. 2006 Oct 1;24(28):4642-60. doi: 10.1200/JCO.2005.04.5260.
8
Hereditary cancer in adults.成人遗传性癌症
Cancer Detect Prev. 1995;19(3):219-33.
9
[Genetic factors involved in cancer susceptibility].[癌症易感性相关的遗传因素]
Gan To Kagaku Ryoho. 2002 Jul;29(7):1255-62.
10
De-mystifying genes: identifying and managing hereditary cancer.揭开基因的神秘面纱:识别与管理遗传性癌症
ONS Connect. 2007;22(8 Suppl):43-4.

引用本文的文献

1
Pre-mRNA Differential 5' Splicing: A Rescue of Functional Protein Properties from Pathogenic Gene Variants and a Lifeline for Fanconi Anemia D1 Patients.前体信使核糖核酸的5' 剪接差异:从致病基因变异中挽救功能性蛋白质特性及范可尼贫血D1型患者的生命线
Int J Mol Sci. 2025 Jul 12;26(14):6694. doi: 10.3390/ijms26146694.
2
Germinal mutations among patients with breast cancer in Colombia: is BRCA3 coming?哥伦比亚乳腺癌患者中的生殖系突变:BRCA3 会出现吗?
Ecancermedicalscience. 2025 Feb 27;19:1859. doi: 10.3332/ecancer.2025.1859. eCollection 2025.
3
Retrospective Study of Genetic Testing Results Reveals Pathogenic Variants Beyond BRCA1/2 in Hereditary Breast and Ovarian Cancer Cases in New Brunswick: Implications for Future Care.
对基因检测结果的回顾性研究揭示了新不伦瑞克省遗传性乳腺癌和卵巢癌病例中除BRCA1/2之外的致病变异:对未来护理的启示。
Cancer Med. 2025 Feb;14(3):e70640. doi: 10.1002/cam4.70640.
4
Multi-locus inherited neoplasia alleles syndromes in cancer: implications for clinical practice.癌症中的多位点遗传性肿瘤等位基因综合征:对临床实践的影响。
Eur J Hum Genet. 2025 Mar;33(3):289-296. doi: 10.1038/s41431-025-01785-1. Epub 2025 Jan 23.
5
Clinicopathological Features and Oncological Outcomes of Germline Partner and Localizer of Breast Cancer 2-Mutated Breast Cancer in Korea.韩国乳腺癌2号基因生殖系伴侣和定位基因(PALB2)突变型乳腺癌的临床病理特征及肿瘤学结局
J Breast Cancer. 2024 Dec;27(6):372-382. doi: 10.4048/jbc.2024.0146.
6
Two recurrent pathogenic/likely pathogenic variants in PALB2 account for half of PALB2 positive families in Slovenia.在斯洛文尼亚,PALB2基因中的两个复发性致病/可能致病变异占PALB2阳性家族的一半。
Hum Genomics. 2024 Dec 18;18(1):137. doi: 10.1186/s40246-024-00706-5.
7
Gain- and loss-of-function alleles within signaling pathways lead to phenotypic diversity among individuals.信号通路中的功能获得性和功能丧失性等位基因导致个体间的表型多样性。
iScience. 2024 Aug 31;27(10):110860. doi: 10.1016/j.isci.2024.110860. eCollection 2024 Oct 18.
8
Potential Role of Glyphosate, Glyphosate-Based Herbicides, and AMPA in Breast Cancer Development: A Review of Human and Human Cell-Based Studies.草甘膦、基于草甘膦的除草剂和 AMPA 在乳腺癌发展中的潜在作用:基于人体和人体细胞的研究综述。
Int J Environ Res Public Health. 2024 Aug 17;21(8):1087. doi: 10.3390/ijerph21081087.
9
Possible link between familial susceptibility to cancer and the level of oxidative stress in thyroid cancer patients.甲状腺癌患者家族性癌症易感性与氧化应激水平之间的潜在联系。
Hered Cancer Clin Pract. 2024 Aug 23;22(1):15. doi: 10.1186/s13053-024-00287-3.
10
Phenotypes of carriers of two mutated alleles in major cancer susceptibility genes.两种主要癌症易感性基因的突变等位基因携带者的表型。
Breast Cancer Res Treat. 2024 Dec;208(3):589-595. doi: 10.1007/s10549-024-07454-z. Epub 2024 Aug 5.