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肝细胞癌的 CT 和 MRI:最新进展。

CT and MRI of hepatocellular carcinoma: an update.

机构信息

Texas Tech University Health Sciences Center, Paul L Foster School of Medicine, 4800 Alberta Avenue, El Paso, TX 79905, USA.

出版信息

Expert Rev Anticancer Ther. 2010 Apr;10(4):507-19. doi: 10.1586/era.10.24.

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and one of the few malignancies with an increasing incidence in the USA. Imaging plays a crucial role in early detection, accurate staging and planning management strategies. Contrast material-enhanced MRI or computed tomography (CT) are the best imaging techniques currently available for the noninvasive diagnosis of HCC. The diagnosis of HCC is strongly dependent on hemodynamic features (arterial hypervascularity and washout in the venous phase) on dynamic imaging, and biopsy is no longer recommended for tumors with classical imaging features prior to treatment. The major challenge for radiologists in imaging cirrhosis is the characterization of hypervascular nodules smaller than 2 cm, which often have nonspecific imaging characteristics. In this review, we discuss the role of CT and MRI in the diagnosis and staging of HCC. The strengths and current limitations of these imaging modalities are highlighted.

摘要

肝细胞癌(HCC)是全球最常见的恶性肿瘤之一,也是美国为数不多的发病率呈上升趋势的恶性肿瘤之一。影像学在早期检测、准确分期和规划管理策略方面发挥着关键作用。对比增强磁共振成像(MRI)或计算机断层扫描(CT)是目前用于 HCC 无创诊断的最佳影像学技术。HCC 的诊断强烈依赖于动态成像的血流动力学特征(动脉期高血管化和静脉期洗脱),并且在治疗前对于具有典型影像学特征的肿瘤,活检已不再推荐。对于影像学医生来说,在肝硬化中对直径小于 2cm 的富血管性结节进行特征描述是主要挑战,因为这些结节的影像学特征往往不具有特异性。在本篇综述中,我们讨论了 CT 和 MRI 在 HCC 的诊断和分期中的作用。强调了这些影像学方法的优势和当前的局限性。

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