Abdollah A, Tampieri D, Melanson D
Department of Neurology and Neurosurgery, Montreal Neurological Hospital, McGill University, Montreal, Que.
Can Assoc Radiol J. 1991 Apr;42(2):130-4.
The condition of a patient with Wilson's disease was evaluated by magnetic resonance imaging (MRI) on initial presentation of the illness. The examination revealed mild atrophy of the superior vermis. Symmetric areas of increased signal intensity on T2-weighted images were detected in the anterior thalami, mesencephalic tectum and tegmentum. Marked symmetric hypointensities appeared in the head of caudate, pallida, substantia nigra and red nuclei. The histopathology of Wilson's disease suggests that these hypointensities may be secondary to the presence of protein-bound copper.
