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[儿童肥厚性肺骨关节病与胸腺癌]

[Hypertrophic pulmonary osteoarthropathy and thymus carcinoma in children].

作者信息

Boukadoum N, Touati R, Kaidi C H, Lankar A, Yaiche M C, Draouat S

机构信息

Service de radiologie, CHU Annaba, Annaba, Algéria.

出版信息

Arch Pediatr. 2010 Jul;17(7):1065-8. doi: 10.1016/j.arcped.2010.03.001. Epub 2010 Apr 18.

Abstract

UNLABELLED

Thymic carcinoma is an uncommon malignant tumor in childhood disease and its association with hypertrophic pulmonary osteoarthropathy remains very rare. So far, only two cases have been reported.

CASE REPORT

During the study of a hospitalized 14-year-old boy suffering from thoracic pain, cough, and finger clubbing, we diagnosed a hypertrophic pulmonary osteoarthropathy caused by paraneoplastic syndrome associated with thymic carcinoma.

COMMENTS

Often associated with chronic respiratory failure, hypertrophic pulmonary osteoarthropathy is rarely observed in childhood diseases. Indeed, its diagnosis is established based on evidence of the combination of finger clubbing and long-bone proliferative periostitis on standard x-ray examination. Thymic carcinoma is a rare neoplasm in children and carries a poor prognosis. Aside from chronic cardiorespiratory problems, the diagnosis of the hypertrophic pulmonary osteoarthropathy in childhood must raise suspicion of a tumoral cause.

摘要

未标注

胸腺癌是儿童疾病中一种罕见的恶性肿瘤,其与肥大性肺性骨关节病的关联仍然非常罕见。迄今为止,仅报告过两例。

病例报告

在对一名因胸痛、咳嗽和杵状指住院的14岁男孩进行研究期间,我们诊断出由与胸腺癌相关的副肿瘤综合征引起的肥大性肺性骨关节病。

评论

肥大性肺性骨关节病常与慢性呼吸衰竭相关,在儿童疾病中很少见。实际上,其诊断基于标准X线检查中杵状指和长骨增殖性骨膜炎相结合的证据。胸腺癌在儿童中是一种罕见的肿瘤,预后较差。除了慢性心肺问题外,儿童肥大性肺性骨关节病的诊断必须引起对肿瘤病因的怀疑。

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