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[类风湿关节炎滑膜的扫描电子显微镜研究]

[Scanning electron microscopy study of the synovial membrane in rheumatoid arthritis].

作者信息

Gaucher A, Faure G, Netter P, Pourel J, Duheille J

出版信息

Sem Hop. 1977 Nov 9;53(38):2095-2100.

PMID:204017
Abstract

A comparative study under the scanning electron microscope of rheumatoid synovial membranes, 5 arthrosic synovial membranes, one tuberculous membrane, and 3 normal synovial membranes showed the pathological changes in the synovial membrane due to rheumatoid arthritis: Inflammatory aspect of the synovial fringes, surrounded by turgid and proliferative villous processes. Granular appearance of the endo-articular surface like a "pebble beach". Dome-shaped synoviocyte layer, standing out well above the subjacent intimal layer, associated with small round cells, also with a raised margin, covering most of the endo-articular surface. Plasma membrane of the superficial synovial cells, covered with numerous and various differentiations and abundant microvillous processes. Reticular deposits or layers, covering the apical poles of the synoviocytes.

摘要

一项在扫描电子显微镜下对类风湿性滑膜、5个关节病滑膜、1个结核性滑膜和3个正常滑膜进行的对比研究显示了类风湿性关节炎导致的滑膜病理变化:滑膜边缘呈现炎症状态,周围是肿胀且增生的绒毛状突起。关节内表面呈颗粒状,类似“卵石滩”。穹顶状的滑膜细胞层,明显高于下方的内膜层,伴有小圆细胞,边缘也隆起,覆盖了大部分关节内表面。表层滑膜细胞的质膜上覆盖着众多不同的分化结构和丰富的微绒毛突起。网状沉积物或层,覆盖滑膜细胞的顶端。

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