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儿童联合疫苗的定价策略及其对收益的影响:百白破疫苗还是沛儿疫苗?

Pricing strategies for combination pediatric vaccines and their impact on revenue: Pediarix or Pentacel?

机构信息

Department of Industrial and Enterprise Systems Engineering, University of Illinois, Urbana, IL, USA.

出版信息

Health Care Manag Sci. 2010 Mar;13(1):54-64. doi: 10.1007/s10729-009-9109-8.

DOI:10.1007/s10729-009-9109-8
PMID:20402282
Abstract

This paper analyzes pricing strategies for pediatric combination vaccines and their impact on the United States pediatric vaccine market. Three pharmaceutical companies compete pairwise with each other over the sale of vaccines containing two or three antigens per injection. Specific emphasis is placed on examining the competition between two pentavalent vaccines: GlaxoSmithKline's Pediarix (DTaP-HepB-IPV) and Sanofi Pasteur's Pentacel (DTaP-IPV/Hib). The main contribution of the paper is to provide a methodology for analyzing pricing strategies of directly competing, partially overlapping, and mutually exclusive combination vaccines in the United States pediatric vaccine market, with the goal of maximizing each pharmaceutical company's expected revenue. The resulting analysis shows that Pentacel is not competitively priced when compared to Pediarix, its strongest competitor, for federal contract prices ending 31 March 2010. Accordingly, Sanofi Pasteur should expect to generate low revenue upon market entry, while Pediarix remains well priced, with GlaxoSmithKline able to generate a high level of revenue at the expense of Sanofi Pasteur. The proposed pricing approach suggests an appropriate price for Pentacel whereby a substantial increase in expected revenue can be realized.

摘要

本文分析了儿科联合疫苗的定价策略及其对美国儿科疫苗市场的影响。三家制药公司两两竞争,销售每针含两种或三种抗原的疫苗。本文特别关注两种五联疫苗之间的竞争:葛兰素史克的潘太欣(DTaP-HepB-IPV)和赛诺菲巴斯德的沛儿(DTaP-IPV/Hib)。本文的主要贡献在于提供了一种分析美国儿科疫苗市场中直接竞争、部分重叠和相互排斥的联合疫苗定价策略的方法,目的是使每家制药公司的预期收入最大化。分析结果表明,与最强竞争对手潘太欣相比,沛儿在截至 2010 年 3 月 31 日的联邦合同价格上没有竞争力。因此,赛诺菲巴斯德预计在进入市场时收入会很低,而潘太欣的定价仍然合理,葛兰素史克可以牺牲赛诺菲巴斯德的利益获得高收入。拟议的定价方法建议沛儿采用适当的价格,从而可以实现预期收入的大幅增长。

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本文引用的文献

1
National, state, and local area vaccination coverage among children aged 19-35 months--United States, 2007.2007年美国19至35个月龄儿童的全国、州和地方疫苗接种覆盖率
MMWR Morb Mortal Wkly Rep. 2008 Sep 5;57(35):961-6.
2
General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP).免疫接种的一般建议:免疫实践咨询委员会(ACIP)的建议。
MMWR Recomm Rep. 2006 Dec 1;55(RR-15):1-48.
3
Engineering the economic value of two pediatric combination vaccines.设计两种儿科联合疫苗的经济价值。
Health Care Manag Sci. 2005 Feb;8(1):29-40. doi: 10.1007/s10729-005-5214-5.
4
Economic value to parents of reducing the pain and emotional distress of childhood vaccine injections.减少儿童疫苗注射的疼痛和情绪困扰对父母的经济价值。
Pediatr Infect Dis J. 2001 Nov;20(11 Suppl):S57-62. doi: 10.1097/00006454-200111001-00009.
5
"Reverse engineering" a formulary selection algorithm to determine the economic value of pentavalent and hexavalent combination vaccines.“逆向工程”一种处方集选择算法,以确定五价和六价联合疫苗的经济价值。
Pediatr Infect Dis J. 2001 Nov;20(11 Suppl):S45-56. doi: 10.1097/00006454-200111001-00008.
6
The effect of additional shots on the vaccine administration process: results of a time-motion study in 2 settings.额外接种对疫苗接种流程的影响:在两种环境下的时间动作研究结果
Am J Manag Care. 2000 Sep;6(9):1038-44.
7
An integer programming model for vaccine procurement and delivery for childhood immunization: a pilot study.用于儿童免疫接种疫苗采购与配送的整数规划模型:一项试点研究。
Health Care Manag Sci. 1999 Jan;2(1):1-9. doi: 10.1023/a:1019011106198.
8
Parents' preferences for outcomes associated with childhood vaccinations.父母对儿童疫苗接种相关结果的偏好。
Pediatr Infect Dis J. 2000 Feb;19(2):129-33. doi: 10.1097/00006454-200002000-00010.
9
How much time is spent on well-child care and vaccinations?在儿童健康护理和疫苗接种上花费了多少时间?
Arch Pediatr Adolesc Med. 1999 Nov;153(11):1154-9. doi: 10.1001/archpedi.153.11.1154.
10
Addressing the challenges to immunization practice with an economic algorithm for vaccine selection.运用疫苗选择经济算法应对免疫实践中的挑战。
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