Lukić Marko, Segec Ana, Segec Igor, Pinotić Ljerka, Ahić Jasminka Milas, Gmajnić Rudika, Pinotić Kresimir, Vcev Aleksandar
Department of Nutrition, University Hospital Center Osijek, Osijek, Croatia.
Coll Antropol. 2010 Mar;34 Suppl 1:55-60.
This study was aimed at monitoring and controlling of body weight in children with diagnosis of celiac disease when established and after introducing gluten-free diet. Prospective clinical study included 42 children with celiac disease whose body weight was measured before introducing gluten-free diet, and after the period of six and 18 months of introducing gluten-free diet. The children were divided into three age groups. The first group consisted of 16 children, 8 females and 8 males in the age from 6 to 18 months, the second group consisted of 14 children, 8 females and 6 males ranging from the age of 20 to 111 months and the third group consisted of 12 children, 6 females and 6 males ranging from the age of 115 to 204 months. The measured body weight was compared with the centile tables of children of the same age. After introducing gluten-free diet the body weight was significantly higher at first, especially at the second control examination in comparison to the centile table of children of the same age and gender When comparing the results at the time of establishing the diagnosis and at the first and second control examination of the body weight of children the results showed no difference concerning gender and the age of children. In conclusion it can be said that is very important to diagnose celiac disease as soon as possible because the introduction of gluten-free diet prevents the pathological conditions mucosal lesion of small intestine and the physical retardation of children.
本研究旨在监测和控制已确诊乳糜泻的儿童在确诊时及引入无麸质饮食后的体重。前瞻性临床研究纳入了42名乳糜泻儿童，在引入无麸质饮食前、引入无麸质饮食6个月和18个月后测量他们的体重。这些儿童被分为三个年龄组。第一组有16名儿童，8名女性和8名男性，年龄在6至18个月之间；第二组有14名儿童，8名女性和6名男性，年龄在20至111个月之间；第三组有12名儿童，6名女性和6名男性，年龄在115至204个月之间。将测量的体重与同年龄儿童的百分位数表进行比较。引入无麸质饮食后，起初体重显著更高，尤其是在第二次对照检查时，与同年龄和性别的儿童百分位数表相比。比较儿童确诊时、首次和第二次体重对照检查的结果，结果显示在儿童性别和年龄方面没有差异。总之，可以说尽早诊断乳糜泻非常重要，因为引入无麸质饮食可预防小肠黏膜病变的病理状况和儿童身体发育迟缓。
