一种新型HLA - Cw*15变异等位基因Cw*1526的鉴定。
Identification of a novel HLA-Cw*15 variant allele, Cw*1526.
作者信息
Wang D, Deng Z
机构信息
Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong, China.
出版信息
Tissue Antigens. 2010 Aug;76(2):158-9. doi: 10.1111/j.1399-0039.2010.01485.x. Epub 2010 Apr 6.
Abstract
A novel human leukocyte antigen (HLA)-Cw15 variant allele was identified in a Chinese Han individual. It differs from the closest allele Cw150201 by single nucleotide change at genomic nt 755 C>G (CDS nt 379 C>G, codon 103 CTG>GTG) in exon 3, which results in an amino acid change Leu103Val.
摘要
在一名中国汉族个体中鉴定出一种新型人类白细胞抗原（HLA）-Cw15变异等位基因。它与最接近的等位基因Cw150201在外显子3的基因组核苷酸755处发生单核苷酸变化C>G（编码区核苷酸379 C>G，密码子103 CTG>GTG），导致氨基酸变化Leu103Val。
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