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通过基因组全长克隆和测序鉴定出一种新型HLA - Cw*04等位基因,即Cw*04010103。

A novel HLA-Cw*04 allele, Cw*04010103, identified by genomic full length cloning and sequencing.

作者信息

Xu Y, Deng Z, Zeng J, Gao S, Wang D

机构信息

Key Laboratory of Shenzhen for Histocompatibility and Immunogenetics, Shenzhen Blood Center, Shenzhen, PR China.

出版信息

Tissue Antigens. 2009 Nov;74(5):453-5. doi: 10.1111/j.1399-0039.2009.01353.x. Epub 2009 Sep 8.

DOI:10.1111/j.1399-0039.2009.01353.x
PMID:19737366
Abstract

A novel human leukocyte antigen-Cw04 allele, Cw04010103, was identified by genomic full length cloning and sequencing from a male Chinese donor. It differs from the closest related allele Cw*04010101 by one nucleotide exchange at nt 1111 (G>A) in intron 3.

摘要

通过对一名中国男性供体进行基因组全长克隆和测序,鉴定出一种新的人类白细胞抗原-Cw04等位基因,即Cw04010103。它与最相近的相关等位基因Cw*04010101在第3内含子的第1111位核苷酸(G>A)处存在一个核苷酸交换。

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引用本文的文献

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