Carr S, Visvanathan V, Hossain T, Uppal S, Chengot P, Woodhead C J
ENT Department, Leeds General Infirmary, UK.
J Laryngol Otol. 2010 Jul;124(7):765-6. doi: 10.1017/S0022215109992635. Epub 2010 Apr 20.
To determine the accuracy of fine needle aspiration cytology conducted within a standard ENT out-patients service (rather than a one-stop neck lump clinic), and also to assess the value of ultrasound guidance during fine needle aspiration cytology.
Retrospective study of all patients undergoing fine needle aspiration cytology of a neck lump, from 2005 to 2008 in Leeds teaching hospitals.
Accuracy of fine needle aspiration cytology, compared with the corresponding histology report of the original surgical specimen, and non-diagnostic fine needle aspiration cytology rates with and without ultrasound.
Fine needle aspiration cytology yielded the following respective sensitivity, specificity and accuracy rates: 85, 91 and 87 per cent for lymph nodes; 80, 93 and 89 for salivary glands; and 52, 80 and 69 for thyroid. The proportion of non-diagnostic procedures was 28 per cent, both with and without ultrasound guidance.
Cytologist-led fine needle aspiration cytology would have reduced the time to diagnosis and the number of clinic visits per patient. Fine needle aspiration cytology was accurate for predicting malignancy in salivary gland and lymph node lesions, and for diagnosing lymph node pathology. Study results did not support the use of ultrasound guidance during fine needle aspiration cytology.
确定在标准耳鼻喉门诊服务（而非一站式颈部肿块诊所）中进行的细针穿刺细胞学检查的准确性，并评估细针穿刺细胞学检查期间超声引导的价值。
对2005年至2008年在利兹教学医院接受颈部肿块细针穿刺细胞学检查的所有患者进行回顾性研究。
将细针穿刺细胞学检查的准确性与原始手术标本的相应组织学报告进行比较，以及有无超声引导下的非诊断性细针穿刺细胞学检查率。
细针穿刺细胞学检查对淋巴结的敏感性、特异性和准确率分别为85%、91%和87%；对唾液腺为80%、93%和89%；对甲状腺为52%、80%和69%。有无超声引导下非诊断性检查的比例均为28%。
由细胞病理学家主导的细针穿刺细胞学检查可减少诊断时间和每位患者的门诊就诊次数。细针穿刺细胞学检查在预测唾液腺和淋巴结病变的恶性肿瘤以及诊断淋巴结病理方面是准确的。研究结果不支持在细针穿刺细胞学检查期间使用超声引导。
Zotero 插件