膀胱膨出在膀胱出口梗阻中起作用吗？

[Does cystocele have a role in bladder outlet obstruction].

作者信息

López González P A, López López A I, López Cubillana P, Escudero Bregante F, Doñate Iñiguez G, Ruiz Morcillo J C, Pérez Albacete M

机构信息

Servicio de Urología, Hospital Virgen de la Arrixaca, Murcia, España.

出版信息

Actas Urol Esp. 2010 Feb;34(2):189-93.

PMID:20403285

Abstract

INTRODUCTION

Controversy exists as to whether cystocele has a causative role in bladder outlet obstruction (BOO).

OBJECTIVE

To assess the relationship between cystocele and bladder outlet obstruction.

MATERIALS AND METHODS

Two hundred women undergoing a urodynamic study from December 2007 to December 2008 were retrospectively assessed. Patients were divided into two groups: Group A: Patients with no cystocele (Grade 0) and Grade I cystocele Group B: Patients with Grade II-IV cystocele.

EXCLUSION CRITERIA

Absence of flowmetry or voided volume < 150 ml. 2. Neurological disorders. 3. History of urogenital surgery. Bladder outlet obstruction was defined as follows: Postvoid residue (PVR) > 20%; peak flow (Qmax) < 15 ml/sec; detrusor pressure at maximum flow (PdetQmax) > 25 cm H2O.

RESULTS

Group A included 64% of patients, and Group B the remaining 36%. A pathological PVR > 20% was found in 26.6% and 40.3% of patients in Group A and Group B respectively (p=0.04). A Qmax < 15 mL/sec was seen in 15.6% and 27.8% of Group A and Group B patients respectively (p=0.03). A PdetQmax > 25 cm H2O was found in 26.3% and 47.8% of Group A and Group B patients respectively (p=0.01).

CONCLUSIONS

A statistically significant association exists between cystocele and bladder outlet obstruction.

摘要

引言

关于膀胱膨出在膀胱出口梗阻（BOO）中是否起致病作用存在争议。

目的

评估膀胱膨出与膀胱出口梗阻之间的关系。

材料与方法

对2007年12月至2008年12月期间接受尿动力学研究的200名女性进行回顾性评估。患者分为两组：A组：无膀胱膨出（0级）和I级膀胱膨出患者；B组：II-IV级膀胱膨出患者。

排除标准

未进行尿流率测定或排尿量<150毫升。2. 神经系统疾病。3. 泌尿生殖系统手术史。膀胱出口梗阻的定义如下：残余尿量（PVR）>20%；最大尿流率（Qmax）<15毫升/秒；最大尿流时逼尿肌压力（PdetQmax）>25厘米水柱。

结果

A组包括64%的患者，B组包括其余36%的患者。A组和B组患者中分别有26.6%和40.3%的患者残余尿量病理性>20%（p = 0.04）。A组和B组患者中分别有15.6%和27.8%的患者最大尿流率<15毫升/秒（p = 0.03）。A组和B组患者中分别有26.3%和47.8%的患者最大尿流时逼尿肌压力>25厘米水柱（p = 0.01）。