Kuo Hann-Chorng
Department of Urology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Urology. 2005 Nov;66(5):1005-9. doi: 10.1016/j.urology.2005.05.047.
To analyze the lower urinary tract symptoms (LUTS) and videourodynamic characteristics of female bladder outlet obstruction (BOO).
Videourodynamic studies were performed in 207 women with signs and symptoms of BOO. Bladder outlet obstruction was defined as the radiologic evidence of bladder outlet narrowing plus a voiding pressure greater than 35 cm H2O and a maximum flow rate less than 15 mL/s or a voiding pressure greater than 40 cm H2O. Women with BOO were categorized into five groups on the basis of the videourodynamic findings. The LUTS and urodynamic parameters were analyzed according to these classifications.
Videourodynamic study revealed bladder neck obstruction in 18 patients (8.7%), urethral sphincter obstruction in 56 (27.1%), pelvic floor muscle obstruction in 106 (51.2%), high-grade pelvic organ prolapse and BOO in 13 (6.3%), and urethral stricture in 14 (6.8%). Urgency frequency was reported by 94% and difficult urination by 57% of the total patients. Among the 17 patients with urinary retention, obstruction was noted at the urethral sphincter in 10, pelvic floor muscle in 5, bladder neck in 1, and urethral stricture in 1. Detrusor overactivity was found in 52.7% of total patients and was most frequent in those with urethral sphincter obstruction (78.6%). Patients with bladder neck obstruction had the highest voiding pressure and lowest maximum flow rate.
Differences in videourodynamic characteristics of women with BOO might be associated with the underlying pathophysiology of the bladder, urethral, and pelvic floor muscle dysfunction.
分析女性膀胱出口梗阻(BOO)的下尿路症状(LUTS)及影像尿动力学特征。
对207例有BOO体征和症状的女性进行影像尿动力学研究。膀胱出口梗阻定义为膀胱出口狭窄的影像学证据,加上排尿压力大于35 cm H₂O且最大尿流率小于15 mL/s,或排尿压力大于40 cm H₂O。根据影像尿动力学检查结果,将患有BOO的女性分为五组。根据这些分类分析LUTS和尿动力学参数。
影像尿动力学研究显示,18例患者(8.7%)存在膀胱颈梗阻,56例(27.1%)存在尿道括约肌梗阻,106例(51.2%)存在盆底肌梗阻,13例(6.3%)存在重度盆腔器官脱垂合并BOO,14例(6.8%)存在尿道狭窄。94%的患者报告有尿急尿频,57%的患者报告有排尿困难。在17例尿潴留患者中,10例梗阻位于尿道括约肌,5例位于盆底肌,1例位于膀胱颈,1例位于尿道狭窄。52.7%的患者存在逼尿肌过度活动,在尿道括约肌梗阻患者中最为常见(78.6%)。膀胱颈梗阻患者的排尿压力最高,最大尿流率最低。
患有BOO的女性影像尿动力学特征的差异可能与膀胱、尿道和盆底肌功能障碍的潜在病理生理学有关。