Brucker Benjamin M, Shah Sagar, Mitchell Sarah, Fong Eva, Nitti Matthew D, Kelly Christopher E, Rosenblum Nirit, Nitti Victor W
Department of Urology, New York University Langone Medical Center, New York, NY, USA.
Female Pelvic Med Reconstr Surg. 2013 Jan-Feb;19(1):46-50. doi: 10.1097/SPV.0b013e31827d87cc.
To characterize the symptoms and urodynamic findings of anatomical bladder outlet obstruction (AO) and functional bladder outlet obstruction (FO) in women and to determine if future endeavors at defining bladder outlet obstruction in women can group these entities together.
Retrospective review of all videourodynamic studies was performed on women from March 2003 to July 2009. Women with diagnosis of obstruction were categorized based on the cause of obstruction into 2 groups: AO and FO. Demographic data, symptoms, and urodynamic findings were compared between the 2 groups.
One hundred fifty-seven women were identified of which 86 (54.8%) were classified as having AO and 71 (45.2%) were classified as having FO. There were no differences in symptoms between the 2 groups. There was no difference (P=0.5789) in the mean detrusor pressure at maximum flow rate Qmax between AO (38.9 cm H20) and FO (41.0 cm H20). There was a difference in the Qmax between AO and FO (10.6 [0-41.7] and 7.4 [0-35.7] mL/s, respectively; P=0.0044), but there was considerable overlap between the values in these 2 groups.
Anatomical bladder outlet obstruction and FO have similar urodynamic voiding pressure findings, but Qmax was statistically significantly lower in AO. However, there is a large overlap in the Qmax values between the 2 groups. Therefore, future studies that attempt to characterize bladder outlet obstruction in women need not exclude either group.
描述女性解剖性膀胱出口梗阻(AO)和功能性膀胱出口梗阻(FO)的症状及尿动力学表现,并确定未来在定义女性膀胱出口梗阻时能否将这些实体归为一类。
对2003年3月至2009年7月期间所有接受视频尿动力学检查的女性进行回顾性研究。根据梗阻原因将诊断为梗阻的女性分为两组:AO组和FO组。比较两组的人口统计学数据、症状及尿动力学表现。
共纳入157名女性,其中86名(54.8%)被归类为AO,71名(45.2%)被归类为FO。两组症状无差异。AO组(38.9 cm H2O)和FO组(41.0 cm H2O)在最大尿流率Qmax时的平均逼尿肌压力无差异(P = 0.5789)。AO组和FO组的Qmax有差异(分别为10.6 [0 - 41.7]和7.4 [0 - 35.7] mL/s;P = 0.0044),但两组数值有相当大的重叠。
解剖性膀胱出口梗阻和FO有相似的尿动力学排尿压力表现,但AO组的Qmax在统计学上显著更低。然而,两组的Qmax值有很大重叠。因此,未来试图描述女性膀胱出口梗阻特征的研究无需排除任何一组。