Department of Neurosurgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea.
J Clin Neurosci. 2010 Jul;17(7):922-4. doi: 10.1016/j.jocn.2009.09.045. Epub 2010 Apr 18.
Tanycytic ependymoma is a rare subtype of ependymoma. Reports of this tumor in neurofibromatosis type 2 (NF-2) are rare. A 16-year-old girl presented with gait disturbance and a palpable neck mass, which had been present for 2 years. MRI revealed an intramedullary lesion within the upper cervical spinal cord, which was removed surgically. Pathological investigation revealed an uncommon form of tanycytic ependymoma associated with NF-2. This rare morphology of tanycytic ependymoma could be misinterpreted as pilocytic astrocytoma or other tumor types that exhibit elongated cells. Increased awareness of this transitional form of intramedullary ependymoma among neurosurgeons and pathologists might avoid incorrect surgical approaches and postoperative treatments.
室管膜下巨细胞型肿瘤是一种罕见的室管膜瘤亚型。神经纤维瘤病 2 型（NF-2）合并此类肿瘤的报告十分罕见。一位 16 岁女孩因步态障碍和可触及的颈部肿块就诊，肿块已存在 2 年。MRI 显示颈髓上段髓内病变，行手术切除。病理检查显示伴有 NF-2 的罕见室管膜下巨细胞型肿瘤。这种罕见的室管膜下巨细胞型肿瘤形态学可能被误诊为毛细胞型星形细胞瘤或其他表现为长形细胞的肿瘤类型。神经外科医生和病理学家对这种脊髓内室管膜瘤的过渡形式有更多的认识，可能会避免错误的手术方法和术后治疗。
