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一名76岁波多黎各男性的室管膜下瘤。

Tanycytic ependymoma in a 76-year-old Puerto Rican male.

作者信息

Ortiz Yvis del Mar, Pérez Berenguer Juan L, Mercado Acosta Juan, Polo Mario, de Jesús-Garces Orlando, Vega Irving E

机构信息

Department of Natural Science and Mathematics, Bayamón Campus, Inter-American University of Puerto Rico Bayamón, PR 00956, USA.

Hato Rey Pathology Lab Caguas, PR 00725, USA ; Department of Pathology, Medical Science Campus, University of Puerto Rico San Juan, PR 00936, USA.

出版信息

Int J Clin Exp Pathol. 2014 Oct 15;7(11):7789-94. eCollection 2014.

Abstract

Ependymoma is a slowly growing tumor in children and young adults originating from the wall of the ventricles or from the spinal canal that is composed of neoplastic ependymal cells. Tanycytic ependymoma is a rare variant of ependymoma usually arising in the intra medullary spine. The World Health Organization classifies the tanycytic ependymoma as a grade II tumor. The diagnosis of tanycytic ependymoma is challenging since the morphology of the lesions resemble those found in schwannoma and astrocytomas. In the present study, we show a case of a 76 years old male with a progressive paraparesis for 8 years, due to a spinal tumor. Radiological and histological studies were used to classify the tumor as tanycytic ependymoma. Therefore, it is important to be aware of tanycytic ependymoma and its immunohistochemistry profile in older patients, especially within the Caribbean Hispanic population. To our knowledge this is the oldest patient known to have this rare tumor and the first case reported in Puerto Rico.

摘要

室管膜瘤是一种在儿童和年轻人中生长缓慢的肿瘤,起源于脑室壁或脊髓管,由肿瘤性室管膜细胞组成。室管膜下巨细胞星形细胞瘤是室管膜瘤的一种罕见变体,通常发生在脊髓髓内。世界卫生组织将室管膜下巨细胞星形细胞瘤归类为二级肿瘤。室管膜下巨细胞星形细胞瘤的诊断具有挑战性,因为病变的形态与神经鞘瘤和星形细胞瘤相似。在本研究中,我们报告了一例76岁男性,因脊柱肿瘤导致进行性双下肢轻瘫8年。通过放射学和组织学研究将肿瘤分类为室管膜下巨细胞星形细胞瘤。因此,了解老年患者尤其是加勒比西班牙裔人群中的室管膜下巨细胞星形细胞瘤及其免疫组化特征非常重要。据我们所知,这是已知患有这种罕见肿瘤的最年长患者,也是波多黎各报道的首例病例。

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