Mikhal'skiĭ A I, Rodionov Iu A, Manton K G, Christensen K, Iashin A I
Adv Gerontol. 2009;22(4):569-87.
Disability prevalence among men and women are investigated using NLTCS surveys conducted in 1982, 1984, 1989, 1994 and 1999 in the US population, on persons older than 65 years, and data from LSADT surveys conducted in 1995, 1997, 1999 and 2001 in the population of the Danish Twins Registry, on persons older than 75 years. In both surveys women are more disabled than men. The probability of becoming disabled and surviving is higher for women than men. The probability of recovering from a disability differs between the sexes statistically insignificant. No time trends are observed in the probabilities of becoming disabled, reversing disability or dying disabled. Calculations show that a decrease in disability prevalence observed in the USA resulted from a decrease in disability prevalence in ages younger than 65 years. Using LSADT data heritability of disability in women older than 75 years is estimated to be 36% (14%; 54%). In men of the same ages the estimate is 11% (0%; 40%) and for both sexes heritability is estimated at 28% (10%; 45%).
利用1982年、1984年、1989年、1994年和1999年在美国进行的针对65岁以上人群的国家长期护理调查(NLTCS)以及1995年、1997年、1999年和2001年在丹麦双胞胎登记处人群中针对75岁以上人群进行的丹麦双胞胎纵向衰老研究(LSADT)的数据,对美国男性和女性的残疾患病率进行了调查。在这两项调查中,女性的残疾程度均高于男性。女性致残和存活的概率高于男性。从残疾中恢复的概率在性别之间差异无统计学意义。在致残、逆转残疾或残疾死亡的概率方面未观察到时间趋势。计算表明,美国残疾患病率的下降是由于65岁以下年龄段残疾患病率的下降所致。利用LSADT数据,75岁以上女性残疾的遗传度估计为36%(14%;54%)。同年龄段男性的估计值为11%(0%;40%),两性的遗传度估计为28%(10%;45%)。