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老年人中眩晕和头晕所致残疾负担:KORA-年龄研究结果

Burden of disability attributable to vertigo and dizziness in the aged: results from the KORA-Age study.

作者信息

Mueller Martin, Strobl Ralf, Jahn Klaus, Linkohr Birgit, Peters Annette, Grill Eva

机构信息

1 Institute for Medical Information Processing, Biometrics and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany 2 German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Universität München, Munich, Germany

1 Institute for Medical Information Processing, Biometrics and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany 2 German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Universität München, Munich, Germany.

出版信息

Eur J Public Health. 2014 Oct;24(5):802-7. doi: 10.1093/eurpub/ckt171. Epub 2013 Nov 8.

DOI:10.1093/eurpub/ckt171
PMID:24213583
Abstract

BACKGROUND

Complaints of vertigo and dizziness are common in primary care in the aged. They can be caused by distinct vestibular disorders, but can also be a symptom in other conditions like non-vestibular sensory loss, vascular encephalopathy or anxiety. The aim of this study was to investigate the specific contribution of vertigo and dizziness to the total burden of disability in aged persons when controlling for the presence of other health conditions.

METHODS

Data originate from the MONICA/KORA study, a population-based cohort. Survivors of the original cohorts who were 65 years and older were examined by telephone interview in 2009. Disability was assessed with the Health Assessment Questionnaire. Logistic regression was used to adjust for potential confounders and additive regression to estimate the contribution of vertigo and dizziness to disability prevalence.

RESULTS

Adjusted for age, sex and other chronic conditions, vertigo and dizziness were associated with disability (odds ratio 1.66, 95% confidence intervals 1.40-1.98). In both men and women between 65 and 79 years, vertigo and dizziness were among the strongest contributors to the burden of disability with a prevalence of 10.5% (6.6 to 15.1) in men and 9.0% (5.7 to 13.0) in women. In men, this effect is stable across all age-groups, whereas it decreases with age in women.

CONCLUSIONS

Vertigo and dizziness independently and relevantly contribute to population-attributable disability in the aged. They are not inevitable consequences of ageing but arise from distinct disease entities. Careful management of vertigo and dizziness might increase population health and reduce disability.

摘要

背景

眩晕和头晕的主诉在老年初级保健中很常见。它们可能由不同的前庭疾病引起,但也可能是其他病症的症状,如非前庭感觉丧失、血管性脑病或焦虑症。本研究的目的是在控制其他健康状况存在的情况下,调查眩晕和头晕对老年人残疾总负担的具体影响。

方法

数据来源于基于人群的队列研究MONICA/KORA研究。2009年通过电话访谈对原队列中65岁及以上的幸存者进行了检查。使用健康评估问卷评估残疾情况。采用逻辑回归调整潜在混杂因素,并使用加法回归估计眩晕和头晕对残疾患病率的影响。

结果

在调整年龄、性别和其他慢性病因素后,眩晕和头晕与残疾相关(比值比1.66,95%置信区间1.40-1.98)。在65至79岁的男性和女性中,眩晕和头晕都是残疾负担的最强贡献因素之一,男性患病率为10.5%(6.6至15.1),女性患病率为9.0%(5.7至13.0)。在男性中,这种影响在所有年龄组中都很稳定,而在女性中则随年龄增长而降低。

结论

眩晕和头晕独立且显著地导致了老年人的人群归因残疾。它们不是衰老的必然结果,而是由不同的疾病实体引起的。对眩晕和头晕进行仔细管理可能会改善人群健康并减少残疾。

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