Furner Sylvia E, Wallace Katrine, Arguelles Lester, Miles Toni, Goldberg Jack
School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA.
J Women Aging. 2010;22(2):83-93. doi: 10.1080/08952841003716071.
This study examined risk factors associated with self-reported health (SRH) in a genetically informative sample of older African American female twins. An interview was conducted with a national sample of 180 African American female twin pairs. Questions included: SRH, demographics, health behaviors, chronic diseases, and functional status. SRH was dichotomized into negative (fair/poor) and positive (good/very good/excellent). Logistic regression for clustered data was used to estimate the odds ratios and 95% confidence intervals. In multivariable analyses, IADL limitations (OR = 1.5, 95% CI = 1.7-2.0) and a chronic disease index (OR = 1.9, 95% CI = 1.4-2.5) were associated with negative SRH. In multivariate within-twin pair analysis, controlling for genetics/shared familial environment, IADLs (OR = 1.8, 95% CI = 1.1-2.7), and increasing numbers of chronic diseases (OR = 2.0, 95% CI = 1.3-3.2) remained significantly associated with negative SRH.
本研究在一个具有遗传信息的老年非裔美国女性双胞胎样本中，考察了与自我报告健康状况（SRH）相关的风险因素。对一个包含180对非裔美国女性双胞胎的全国性样本进行了访谈。问题包括：自我报告健康状况、人口统计学特征、健康行为、慢性疾病和功能状态。自我报告健康状况被分为消极（一般/较差）和积极（良好/非常好/优秀）两类。使用聚类数据的逻辑回归来估计比值比和95%置信区间。在多变量分析中，日常生活活动受限（比值比=1.5，95%置信区间=1.7 - 2.0）和慢性病指数（比值比=1.9，95%置信区间=1.4 - 2.5）与消极的自我报告健康状况相关。在双胞胎对内的多变量分析中，控制了遗传因素/共享的家庭环境后，日常生活活动（比值比=1.8，95%置信区间=1.1 - 2.7）以及慢性病数量的增加（比值比=2.0，95%置信区间=1.3 - 3.2）仍然与消极的自我报告健康状况显著相关。
