Kharitonova L A, Kosareva T M, Kochetova E A, Shakarian K A
Eksp Klin Gastroenterol. 2010(1):20-4.
Although that the first reports of cholesterosis gall bladder were in the second half of the XIX century, there is still insufficient information about the frequency of its detection in children. According to some researchers, this disease was detected in patients aged 13 to 14 years. In other periods of childhood gallbladder cholesterosis is considered to be casuistic rarity. Multiyear study conducted by the authors in the study of diseases of biliary tract showed that almost a third of children had combined with cholelithiasis with gallbladder cholesterosis. However, prior to cholecystectomy is diagnosed only 5% of children. In connection with this the aim of our work was to learn the peculiarities of the clinical picture and morphological changes in children at gallbladder cholesterosis. Material and methods. There were observed 54 children with gallbladder cholesterosis (GBC) aged from 1 year to 15 years (20 girls, 34 boys) . The diagnosis was confirmed histologically in the walls of GB. Gallbladder cholesterosis was differentiated from polyps and concrements of GB in the performance of traditional and endoscopic ultrasound. According to testimony performed endoscopic retrograde cholangiopancreatography (ERCP) and magnetic resonance imaging of the abdominal cavity. The material was processed statistically using a specially program developed by Medstat. Results. There were showed clinical course features and morphological picture of the gallbladder wall. There were brought the attention of pediatricians to the reversibility of the pathological process in childhood, which suggests alternative methods of treatment in gallbladder cholesterosis the in children--traditional treatment.
尽管关于胆囊胆固醇沉着症的首次报告出现在19世纪后半叶,但关于其在儿童中检出频率的信息仍然不足。据一些研究人员称,这种疾病在13至14岁的患者中被检测到。在儿童期的其他阶段,胆囊胆固醇沉着症被认为是偶发的罕见疾病。作者在胆道疾病研究中进行的多年研究表明,几乎三分之一的儿童患有胆囊胆固醇沉着症合并胆结石。然而,在胆囊切除术之前,只有5%的儿童被诊断出来。鉴于此,我们工作的目的是了解儿童胆囊胆固醇沉着症的临床表现特点和形态学变化。材料与方法。观察了54例年龄在1岁至15岁之间的胆囊胆固醇沉着症(GBC)儿童(20名女孩,34名男孩)。通过胆囊壁组织学检查确诊。在传统超声和内镜超声检查中,将胆囊胆固醇沉着症与胆囊息肉和结石区分开来。根据检查结果进行内镜逆行胰胆管造影(ERCP)和腹腔磁共振成像。使用Medstat开发的专门程序对材料进行统计处理。结果。展示了胆囊壁的临床病程特征和形态学表现。提醒儿科医生注意儿童期病理过程的可逆性,这表明儿童胆囊胆固醇沉着症的替代治疗方法——传统治疗。