State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, People's Republic of China.
J Org Chem. 2010 May 21;75(10):3526-8. doi: 10.1021/jo1005125.
Gold-catalyzed intramolecular reactions of 3-alkynyl-bearing indoles with diol groups lead to the formation of highly functionalized 3-allenylindoles with high efficiency. The reaction likely proceeds by a new gold-catalyzed cascade cyclization/heterolytic fragmentation/elimination reactions, which results in 1,5-indole migration and C-3 allenylation of indole moiety.
金催化的 3-炔基吲哚与二醇基团的分子内反应以高效率生成高度官能化的 3-烯丙基吲哚。该反应可能通过新的金催化级联环化/均裂断裂/消除反应进行，导致 1,5-吲哚迁移和吲哚部分的 C-3 烯丙基化。
