Rosenberg Neil, Chen Michael, Prabhakaran Shyam
Department of Neurological Sciences, Rush University Medical Center, 1725 W Harrison Street, Suite 1106, Chicago, IL 60612, USA.
Recent Pat CNS Drug Discov. 2010 Jun;5(2):118-34. doi: 10.2174/157488910791213176.
The past decade has witnessed an explosion of devices available for treating acute ischemic stroke. Here, we review a range of recently patented devices and the data supporting their use. These include devices to enhance thrombolysis, thrombectomy devices, stents, devices for augmenting global brain tissue perfusion, and devices that provide neuroprotection after stroke. We discuss specific design elements of these devices and directions for future research. Ultimately, individually tailored combinations of these devices will likely prove most useful in treating patients with acute ischemic stroke.
在过去十年中,用于治疗急性缺血性中风的设备激增。在此,我们回顾一系列近期获得专利的设备以及支持其使用的数据。这些设备包括增强溶栓作用的设备、取栓设备、支架、增强全脑组织灌注的设备以及中风后提供神经保护的设备。我们讨论这些设备的具体设计要素以及未来研究方向。最终,这些设备的个性化定制组合可能在治疗急性缺血性中风患者时最为有用。