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淋巴管结扎和死腔关闭预防乳腺癌根治术和腋窝清扫术后血清肿的形成:一项随机试验。

Prevention of seroma formation after mastectomy and axillary dissection by lymph vessel ligation and dead space closure: a randomized trial.

机构信息

Department of Oncological Surgery, Zhongnan Hospital, Wuhan University, Hubei, China.

出版信息

Am J Surg. 2010 Sep;200(3):352-6. doi: 10.1016/j.amjsurg.2009.10.013. Epub 2010 Apr 20.

DOI:10.1016/j.amjsurg.2009.10.013
PMID:20409509
Abstract

INTRODUCTION

We aimed to reduce the incidence of seroma formation by altering surgical technique.

METHODS

Two hundred one breast cancer patients were randomly divided into 2 arms: arm 1 was operated on using an altered surgical technique, which is to ligate all of the tissue connecting axillary vein bundles to the specimen, to suture the anterior edge of the latissimus dorsi to the chest wall, and to fix the skin flap to the underlying muscle by subcutaneous sutures; arm 2 was operated on using the conventional technique.

RESULTS

The drainage volume, in the initial 3 days, for patients in arm 1 was significantly less than that for patients in arm 2 (P < .01). The duration of drainage in arm 1 was shorter than that in arm 2 (P < .01). The incidence of seroma formation in arm 1 (2%) was significantly less than that in arm 2 (14%) (P < .01).

CONCLUSION

The modified operating technique is an effective approach to reducing the incidence of seroma formation after mastectomy and axillary dissection.

摘要

简介

我们旨在通过改变手术技术来降低血清肿形成的发生率。

方法

201 例乳腺癌患者随机分为 2 组:第 1 组采用改良手术技术,即结扎所有连接腋静脉束至标本的组织,缝合背阔肌前缘至胸壁,并通过皮下缝线将皮瓣固定在下面的肌肉上;第 2 组采用常规技术进行手术。

结果

第 1 组患者在最初 3 天的引流量明显少于第 2 组(P <.01)。第 1 组引流时间短于第 2 组(P <.01)。第 1 组(2%)血清肿形成的发生率明显低于第 2 组(14%)(P <.01)。

结论

改良手术技术是减少乳腺癌改良根治术和腋窝清扫术后血清肿形成的有效方法。

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