Mamalis N, Craig M T, Coulter V L, Lundergan M K, Olson R J
Intermountain Ocular Research Center, University of Utah School of Medicine, Salt Lake City.
J Cataract Refract Surg. 1991 Mar;17(2):163-7. doi: 10.1016/s0886-3350(13)80246-5.
We analyzed 740 penetrating keratoplasty specimens received at the Intermountain Ocular Research Center from 1981 through 1988. These corneal specimens were categorized by clinical indications for removal and pathologic confirmation of the clinical findings. Keratoconus was the most common indication for a penetrating keratoplasty (22.8%). This was closely followed by pseudophakie bullous keratopathy (21.8%), regraft (13.2%), scarring (8.9%), aphakic bullous keratopathy (6.4%), and Fuchs' endothelial dystrophy (5.8%). Since 1984, pseudophakic bullous keratopathy has surpassed keratoconus as the most common indication for penetrating keratoplasty (27.3% vs. 20.2%). Pseudophakic bullous keratopathy was found more commonly than keratoconus in each of the last four years of this study. The most common type of intraocular lens associated with pseudophakic bullous keratopathy was an anterior chamber lens (52.8%), with iris-fixated (26.7%) and posterior chamber (17.4%) lenses seen less frequently.
我们分析了1981年至1988年间在山间眼科研中心接收的740份穿透性角膜移植标本。这些角膜标本根据切除的临床指征和临床发现的病理确认进行分类。圆锥角膜是穿透性角膜移植最常见的指征（22.8%）。紧随其后的是人工晶状体性大疱性角膜病变（21.8%）、再次移植（13.2%）、瘢痕形成（8.9%）、无晶状体性大疱性角膜病变（6.4%）和富克斯内皮营养不良（5.8%）。自1984年以来，人工晶状体性大疱性角膜病变已超过圆锥角膜，成为穿透性角膜移植最常见的指征（27.3%对20.2%）。在本研究的最后四年中，每年人工晶状体性大疱性角膜病变的发现都比圆锥角膜更常见。与人工晶状体性大疱性角膜病变相关的最常见类型的人工晶状体是前房型人工晶状体（52.8%），虹膜固定型（26.7%）和后房型（17.4%）人工晶状体较少见。
