Mamalis N, Anderson C W, Kreisler K R, Lundergan M K, Olson R J
Intermountain Ocular Research Center, University of Utah School of Medicine, Salt Lake City.
Arch Ophthalmol. 1992 Oct;110(10):1409-11. doi: 10.1001/archopht.1992.01080220071023.
The indications for penetrating keratoplasty have changed over the past several years. Nine hundred ninety-nine penetrating keratoplasty specimens from 1981 through 1990 were analyzed. Overall, keratoconus was the most common indication for penetrating keratoplasty (24.2%). This was followed by pseudophakic bullous keratopathy (23.0%), regraft (13.1%), scarring (8.2%), and Fuchs' endothelial dystrophy (5.8%). Pseudophakic bullous keratopathy was the most common indication for penetrating keratoplasty in each year from 1984 through 1989 with a peak in 1987 (33%). Since 1987, the number of pseudophakic bullous keratopathy cases has decreased; and in 1990, keratoconus (33.1%) surpassed pseudophakic bullous keratopathy (24.1%) as the most common indication for penetrating keratoplasty. This decreasing incidence of pseudophakic bullous keratopathy may reflect the discontinued use of closed-looped anterior chamber and iris-plane intraocular lenses most commonly associated with this complication.
在过去几年中，穿透性角膜移植术的适应证发生了变化。对1981年至1990年的999例穿透性角膜移植术标本进行了分析。总体而言，圆锥角膜是穿透性角膜移植术最常见的适应证（24.2%）。其次是人工晶状体性大泡性角膜病变（23.0%）、再次移植（13.1%）、瘢痕形成（8.2%）和富克斯内皮营养不良（5.8%）。1984年至1989年期间，人工晶状体性大泡性角膜病变是每年穿透性角膜移植术最常见的适应证，1987年达到高峰（33%）。自1987年以来，人工晶状体性大泡性角膜病变的病例数有所减少；1990年，圆锥角膜（33.1%）超过人工晶状体性大泡性角膜病变（24.1%），成为穿透性角膜移植术最常见的适应证。人工晶状体性大泡性角膜病变发病率的下降可能反映了最常与该并发症相关的闭环前房和虹膜平面人工晶状体的停用。
