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血清抗体及感染猪圆环病毒 2 型在免疫和自然感染后备母猪初乳和常乳中的排放。

Serum antibodies and shedding of infectious porcine circovirus 2 into colostrum and milk of vaccinated and unvaccinated naturally infected sows.

机构信息

Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Minas Gerais, Brazil.

出版信息

Vet J. 2011 May;188(2):240-2. doi: 10.1016/j.tvjl.2010.03.023. Epub 2010 Apr 20.

DOI:10.1016/j.tvjl.2010.03.023
PMID:20409736
Abstract

Serum antibodies and shedding of porcine circovirus type 2 (PCV2) into lacteal secretions were examined in naturally infected sows. Total (TA) and neutralising (NA) antibodies against PCV2 were evaluated in serum and colostrum from 20 vaccinated (Vac) and 21 unvaccinated (N-vac) sows. Anti-PCV2 IgA titres and PCV2 infectious titres were determined in colostrum and milk. All sows had high TA and NA levels in serum and colostrum. Infectious PCV2 was detected in 22/41 colostrum samples (7/20 Vac and 15/21N-Vac sows) and 5/20 milk samples (1/5 Vac and 4/15N-Vac sows). Anti-PCV2 IgA was found in high levels in colostrum and varying levels in milk. Infectious PCV2 may be present in milk and colostrum of naturally infected sows, even in the presence of NA.

摘要

本研究检测了自然感染猪圆环病毒 2 型(PCV2)的母猪血清抗体和乳脂分泌中的病毒脱落情况。从 20 头免疫(Vac)和 21 头未免疫(N-vac)母猪的血清和初乳中评估了针对 PCV2 的总(TA)和中和(NA)抗体。在初乳和牛奶中测定了抗 PCV2 IgA 滴度和 PCV2 感染性滴度。所有母猪的血清和初乳中均具有高 TA 和 NA 水平。在 22/41 份初乳样本(7/20 Vac 和 15/21N-Vac 母猪)和 5/20 份牛奶样本(1/5 Vac 和 4/15N-Vac 母猪)中检测到感染性 PCV2。在初乳和牛奶中均发现高水平的抗 PCV2 IgA。即使存在 NA,感染性 PCV2 也可能存在于自然感染母猪的牛奶和初乳中。

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