溶菌酶稳定的金荧光团簇：合成及作为 Hg(2+)传感器的应用。
Lysozyme-stabilized gold fluorescent cluster: Synthesis and application as Hg(2+) sensor.
机构信息
Department of Chemistry, University of Illinois, Urbana-Champaign, Urbana, Illinois 61801, USA.
出版信息
Analyst. 2010 Jun;135(6):1406-10. doi: 10.1039/c0an00046a. Epub 2010 Apr 22.
Abstract
Highly fluorescent gold clusters have been synthesized in basic aqueous solution by using lysozyme as reducing and stabilizing agents. The lysozyme-stabilized gold fluorescent clusters (LsGFC) have an average size of 1 nm and emission approximately 657 nm. The fluorescence could be specifically quenched by Hg(2+), so the LsGFC can be used as a sensor for sensitive and selective Hg(2+) detection with a detection limit of 10 nM.
摘要
高荧光金纳米簇已经通过使用溶菌酶作为还原剂和稳定剂在碱性水溶液中合成。溶菌酶稳定的金荧光纳米簇（LsGFC）的平均尺寸为 1nm，发射波长约为 657nm。荧光可以被 Hg(2+)特异性猝灭，因此 LsGFC 可以用作一种传感器，用于灵敏和选择性检测 Hg(2+)，检测限为 10 nM。
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