临床医学和临床试验。
Clinical medicine and clinical trials.
机构信息
Department of Radiation Oncology, UNC/Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7512, USA.
出版信息
Oncologist. 2010;15(4):382-7. doi: 10.1634/theoncologist.2009-S107.
Abstract
The author discusses the role of clinical trials in clinical medicine.
摘要
作者讨论了临床试验在临床医学中的作用。
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本文引用的文献
1
Variations in target volume definition for postoperative radiotherapy in stage III non-small-cell lung cancer: analysis of an international contouring study.术后放疗中 III 期非小细胞肺癌靶区定义的变化：一项国际勾画研究分析。
Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):1106-13. doi: 10.1016/j.ijrobp.2009.02.072. Epub 2009 Jun 27.
2
Variability of target and normal structure delineation for breast cancer radiotherapy: an RTOG Multi-Institutional and Multiobserver Study.乳腺癌放疗中靶区和正常结构勾画的变异性：一项RTOG多机构多观察者研究
Int J Radiat Oncol Biol Phys. 2009 Mar 1;73(3):944-51. doi: 10.1016/j.ijrobp.2008.10.034.
3
The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma.TME试验，中位随访6年：可切除直肠癌放疗患者的局部控制率提高，但无生存获益。
Ann Surg. 2007 Nov;246(5):693-701. doi: 10.1097/01.sla.0000257358.56863.ce.
4
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group.厄洛替尼联合吉西他滨与吉西他滨单药治疗晚期胰腺癌患者的比较：加拿大国家癌症研究所临床试验组的一项III期试验
J Clin Oncol. 2007 May 20;25(15):1960-6. doi: 10.1200/JCO.2006.07.9525. Epub 2007 Apr 23.
5
Extracranial radiosurgery (stereotactic body radiation therapy) for oligometastases.用于寡转移灶的颅外放射外科治疗（立体定向体部放射治疗）
Semin Radiat Oncol. 2006 Apr;16(2):77-84. doi: 10.1016/j.semradonc.2005.12.003.
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Stereotactic body radiation therapy for extracranial oligometastases: does the sword have a double edge?立体定向体部放射治疗用于颅外寡转移瘤：这把剑是否有双刃剑效应？
Semin Radiat Oncol. 2006 Apr;16(2):67-76. doi: 10.1016/j.semradonc.2005.12.002.
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Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials.早期乳腺癌放疗及手术范围差异对局部复发和15年生存率的影响：随机试验综述
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JAMA. 2002 Jan 16;287(3):321-8. doi: 10.1001/jama.287.3.321.
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Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction.胃癌或胃食管交界腺癌术后同步放化疗与单纯手术的比较。
N Engl J Med. 2001 Sep 6;345(10):725-30. doi: 10.1056/NEJMoa010187.
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Semin Radiat Oncol. 2001 Jan;11(1):3-15. doi: 10.1053/srao.2001.18099.
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