Lertsinudom Sunee, Johns Nutjaree Pratheepawanit, Chanthawong Suthan, Boonsawat Watchara, Samosorn Chanee
Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand.
J Med Assoc Thai. 2010 Mar;93(3):373-7.
The present study assessed the validity and reliability of the Thai Mini AQLQ in the Easy Asthma Clinic, Srinagarind Hospital.
The present study used a cross sectional design, using an interview method by two trained-interviewers. The Thai Mini AQLQ consists of 15 items categorized into Symptoms, Activities, Emotions, Environment and Overall Scores. Scores range from 0 to 7 with higher scores meaning better quality of life. Cronbach's alpha was used to test for internal consistency reliability. Known group validation regarding asthma control was analyzed by the t-test and multiple regression, adjusting for age, gender and education.
Of 168 patients recruited, 113 were controlled and, of these 55 were uncontrolled asthma patients, with an average age 53 +/- 13 years. Patients with controlled asthma reported significantly better scores in all domains compared with uncontrolled asthma: symptoms 6.6 +/- 0.54 vs. 4.7 +/- 1.14, p < 0.001; Activity 6.7 +/- 0.57 vs. 5.0 +/- 1.36, p < 0.001; emotion 6.4 +/- 0.91 vs. 4.6 +/- 1.67, p < 0.001; environment 5.3 +/- 1.10 vs. 4.1 +/- 1.24, p < 0.001 and overall scores 6.3 +/- 0.51 vs. 4.6 +/- 0.96, p < 0.001. Adjusting for age, gender and education using multiple regression, there was also a significant difference in all domains of Thai Mini AQLQ between the controlled and uncontrolled asthma patients. Internal consistency reliability was within the acceptable range (> 0.7) for all domains, except environment (overall 0.910; symptoms 0.855; activities 0.886; emotions 0.765 and environment 0.616).
Thai Mini AQLQ has known to be reliable and valid. Further study on test-retest reliability and responsiveness to change are warranted.
本研究评估了泰国版简易哮喘生活质量问卷(Thai Mini AQLQ)在诗里拉吉医院简易哮喘诊所的有效性和可靠性。
本研究采用横断面设计,由两名经过培训的访谈员采用访谈法进行。泰国版简易哮喘生活质量问卷由15个项目组成,分为症状、活动、情绪、环境和总体得分。得分范围为0至7分,分数越高表明生活质量越好。采用克朗巴哈系数(Cronbach's alpha)检验内部一致性可靠性。通过t检验和多元回归分析哮喘控制情况的已知组效度,并对年龄、性别和教育程度进行校正。
在招募的168名患者中,113名病情得到控制,其中55名是未得到控制的哮喘患者,平均年龄为53±13岁。与未得到控制的哮喘患者相比,病情得到控制的哮喘患者在所有领域的得分均显著更高:症状方面,分别为6.6±0.54和4.7±1.14,p<0.001;活动方面,分别为6.7±0.57和5.0±1.36,p<0.001;情绪方面,分别为6.4±0.91和4.6±1.67,p<0.001;环境方面,分别为5.3±1.10和4.1±1.24,p<0.001;总体得分方面,分别为6.3±0.51和4.6±0.96,p<0.001。通过多元回归对年龄、性别和教育程度进行校正后,病情得到控制和未得到控制的哮喘患者在泰国版简易哮喘生活质量问卷的所有领域也存在显著差异。除环境领域外,所有领域的内部一致性可靠性均在可接受范围内(>0.7)(总体为0.910;症状为0.855;活动为0.886;情绪为0.765;环境为0.616)。
已知泰国版简易哮喘生活质量问卷可靠且有效。有必要进一步研究其重测可靠性和对变化的反应性。