Kumamoto Taisuke, Nishi Masaaki
Division of Anesthesia, Kumamoto Rousai Hospital, Yatsushiro 866-8533.
Masui. 2010 Apr;59(4):514-8.
Renal cell carcinoma (RCC) is characterized by a propensity to invade the inferior vena cava (IVC) via the renal vein. It is estimated that such tumor thrombus extension is observed in 4-10% of cases. As the presence of tumor thrombus has not been shown to be a determinant of survival, surgical resection remains the mainstay for treatment. A 57-year-old woman with renal cell carcinoma extending into the right atrium was scheduled for radical nephrectomy and thrombectomy under cardiopulmonary bypass. There was a high possibility of massive bleeding and pulmonary embolism resulting in sudden death during surgical manipulation. Preparing for pulmonary embolism, at the beginning of the operation, a median sternotomy was perfomed to enable us to initiate the CPB immediately. Moreover transesophageal echocardiography (TEE) was perfomed during the operation to detect pulmonary embolism and to recognize the position of the thrombus. In this case, we can detect the cephalad extent of the thrombus during surgical manipulation by continuous TEE monitoring, and notify the information to the surgeons. The use of TEE allowed rapid initiation of CPB before the onset of pulmonary embolism. The monitor showed no signs of pulmonary embolism, and the operation proceeded uneventfully. We recognized the diagnostic power of TEE and its crucial role in a patient having tumor thrombus extending to the IVC.
肾细胞癌(RCC)的特点是易于通过肾静脉侵犯下腔静脉(IVC)。据估计,在4%-10%的病例中可观察到这种肿瘤血栓延伸。由于肿瘤血栓的存在尚未被证明是生存的决定因素,手术切除仍然是主要的治疗方法。一名57岁的肾细胞癌延伸至右心房的女性计划在体外循环下进行根治性肾切除术和血栓切除术。在手术操作过程中,发生大出血和肺栓塞导致猝死的可能性很高。为应对肺栓塞,在手术开始时,进行了正中胸骨切开术,以便我们能够立即启动体外循环。此外,在手术过程中进行了经食管超声心动图(TEE)检查,以检测肺栓塞并识别血栓的位置。在本病例中,我们可以通过持续的TEE监测在手术操作过程中检测血栓的头端范围,并将信息告知外科医生。TEE的使用使我们能够在肺栓塞发生前迅速启动体外循环。监测器未显示肺栓塞迹象,手术顺利进行。我们认识到TEE的诊断能力及其在肿瘤血栓延伸至IVC患者中的关键作用。