Shimono H, Kadota Y, Uchiyama H, Miyamoto Y, Kawasaki K, Yoshimura N
Department of Anesthesiology & Critical Care Medicine, Kagoshima University School of Medicine.
Masui. 1999 Apr;48(4):404-9.
A 70-year-old male with renal cell carcinoma extending into the retrohepatic inferior vena cava was scheduled for radical nephrectomy with vena caval resection under general anesthesia. He had received partial gastrectomy for gastric cancer twelve years before. Computed tomography and inferior vena cavography confirmed that the vena cava was almost completely occluded and that a collateral venous network was well established. It was considered that the surgical approach to the retrohepatic cavals area was technically very difficult, and that there was a high possibility of a pulmonary embolus during the surgical manipulation. To prevent a pulmonary embolus and get good control of the vena cava above the tumor and below the hepatic vein, we decided to use a partial cardiopulmonary bypass (CPB) until the vena cava was clamping above the tumor. Anesthesia was induced with propofol and fentanyl, and maintained with fentanyl and isoflurane-N2O-O2. In the partial CPB blood from the hepatic vein was drained from the inferior vena cava cannula through right atrium, oxygenated by microporus membrane oxygenator, and returned to the left femoral artery. Cannulation to drain the venous circulation entering the vena cava below the tumor was abandoned because the extensive collateral venous network ultimately drains into the superior vena cava. The partial CPB time was 90 min, and the bladder temperature during the CPB was 35-36 degrees C. During the 7.3 hr procedure, the pulmonary embolus did not occur and the total blood loss was 5515 ml. The patient made an uncomplicated recovery and was discharged 30 days after the operation. This newly reported partial-CPB method may be safe and effective for the management under anesthesia of other patients.
一名70岁男性,肾细胞癌已侵犯至肝后下腔静脉,计划在全身麻醉下行根治性肾切除术并切除腔静脉。他12年前曾因胃癌接受过部分胃切除术。计算机断层扫描和下腔静脉造影证实下腔静脉几乎完全闭塞,且已建立了完善的侧支静脉网络。认为手术进入肝后腔静脉区域在技术上非常困难,且手术操作过程中发生肺栓塞的可能性很高。为预防肺栓塞并良好控制肿瘤上方和肝静脉下方的腔静脉,我们决定在肿瘤上方夹住腔静脉之前使用部分体外循环(CPB)。用丙泊酚和芬太尼诱导麻醉,并用芬太尼和异氟烷 - N₂O - O₂维持麻醉。在部分CPB过程中,来自肝静脉的血液通过右心房从下腔静脉插管引出,经微孔膜氧合器氧合后,返回左股动脉。由于广泛的侧支静脉网络最终汇入上腔静脉,因此放弃了对肿瘤下方进入腔静脉的静脉循环进行引流的插管操作。部分CPB时间为90分钟,CPB期间膀胱温度为35 - 36摄氏度。在长达7.3小时的手术过程中,未发生肺栓塞,总失血量为5515毫升。患者恢复顺利,术后30天出院。这种新报道的部分CPB方法可能对其他患者的麻醉管理安全有效。