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[念珠菌属在血液、血管导管、尿液和粪便中的分离率及药敏情况]

[Isolation rate and susceptibilities of Candida species from blood, vascular catheter, urine and stool].

作者信息

Tashiro Masato, Murakami Hinako, Yoshizawa Sadako, Tateda Kazuhiro, Yamaguchi Keizo

机构信息

Department of Microbiology, Toho University School of Medicine.

出版信息

Kansenshogaku Zasshi. 2010 Mar;84(2):187-92. doi: 10.11150/kansenshogakuzasshi.84.187.

DOI:10.11150/kansenshogakuzasshi.84.187
PMID:20420164
Abstract

We evaluated species distribution and antifungal susceptibility of Candida isolates during 2002-2008. Of 177 Candida isolates from blood, species distribution was 90 (51%) Candida albicans, 30 (17%) C. parapsilosis, 22 (12%) C. glabrata, 6 (3%) C. tropicalis and 29 (16%) other Candida spp.. Of 162 Candida isolates from vascular catheter, species distribution was 87 (54%) C. albicans, 14 (9%) C. parapsilosis, 36 (22%) C. glabrata, 5 (3%), C. tropicalis, 2 (1%) C. krusei and 18 (11%) other Candida spp.. Of 1889 Candida isolates from urine, species distribution was 1165 (62%) C. albicans, 22 (1%) C. parapsilosis, 484 (26%) C. glabrata, 83 (4%) C. tropicalis, 26 (1%) C. krusei and 109 (6%) other Candida spp.. Of 782 Candida isolates from stool, species distribution was 425 (54%) C. albicans, 3 (1%) C. parapsilosis, 103 (13%) C. glabrata, 28 (4%) C. tropicalis, 5 (1%), C. krusei and 218 (28%) other Candida spp.. Both C. albicans and non-Candida spp. isolated from urine increased slightly over the past 7 years. Flucytosine, fluconazole, itraconazole and micafungin still have strong activity against Candida isolates.

摘要

我们评估了2002年至2008年期间念珠菌分离株的物种分布和抗真菌药敏情况。在177株血液来源的念珠菌分离株中,物种分布为:白色念珠菌90株(51%),近平滑念珠菌30株(17%),光滑念珠菌22株(12%),热带念珠菌6株(3%),其他念珠菌属29株(16%)。在162株血管导管来源的念珠菌分离株中,物种分布为:白色念珠菌87株(54%),近平滑念珠菌14株(9%),光滑念珠菌36株(22%),热带念珠菌5株(3%),克柔念珠菌2株(1%),其他念珠菌属18株(11%)。在1889株尿液来源的念珠菌分离株中,物种分布为:白色念珠菌1165株(62%),近平滑念珠菌22株(1%),光滑念珠菌484株(26%),热带念珠菌83株(4%),克柔念珠菌26株(1%),其他念珠菌属109株(6%)。在782株粪便来源的念珠菌分离株中,物种分布为:白色念珠菌425株(54%),近平滑念珠菌3株(1%),光滑念珠菌103株(13%),热带念珠菌28株(4%),克柔念珠菌5株(1%),其他念珠菌属218株(28%)。过去7年中,尿液中分离出的白色念珠菌和非白色念珠菌属均略有增加。氟胞嘧啶、氟康唑、伊曲康唑和米卡芬净对念珠菌分离株仍有较强活性。

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