Mohamed Waleed Z
Nephrology Division, Medical Department, Dawmat Aljandal General Hospital, Aljouf, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2010 May;21(3):548-54.
Hepatitis C virus (HCV) has been a significant problem in hemodialysis (HD) patients. In general, it carries significant morbidity including liver cirrhosis, liver cell failure and hepatoma. The study was conducted on 36 seronegative HD patients. All patients were managed with strict application of infection control guidelines as well as isolation of HCV-positive patients. None of the patients received any blood transfusions and were managed with iron and erythropoietin. After five years of follow-up, we found that the incidence of HCV seroconversion was zero. Our study further suggests that following infection control guidelines, isolation of seropositive patients and minimizing blood transfusions can help in prevention of HCV transmission among HD patients.
丙型肝炎病毒（HCV）一直是血液透析（HD）患者面临的一个重大问题。一般来说，它会引发包括肝硬化、肝细胞衰竭和肝癌在内的严重疾病。该研究针对36名血清学阴性的血液透析患者展开。所有患者均严格按照感染控制指南进行管理，并对HCV阳性患者进行隔离。所有患者均未接受任何输血治疗，而是接受铁剂和促红细胞生成素治疗。经过五年的随访，我们发现HCV血清学转换的发生率为零。我们的研究进一步表明，遵循感染控制指南、隔离血清学阳性患者以及尽量减少输血有助于预防血液透析患者之间的HCV传播。
