Grothe Cibele, da Silva Belasco Angélica Gonçalves, de Cássia Bittencourt Ana Rita, Vianna Lucila Amaral Carneiro, de Castro Cintra Sesso Ricardo, Barbosa Dulce Aparecida
Departamento de Enfermagem, Universidade Federal de São Paulo, Brazil.
Rev Lat Am Enfermagem. 2010 Jan-Feb;18(1):73-80. doi: 10.1590/s0104-11692010000100012.
This study evaluated the incidence and risk factors of bloodstream infection (BSI) among patients with a double-lumen central venous catheter (CVC) for hemodialysis (HD) and identified the microorganisms isolated from the bloodstream. A follow-up included all patients (n=156) who underwent hemodialysis by double-lumen CVC at the Federal University of São Paulo-UNIFESP, Brazil, over a one-year period. From the group of patients, 94 presented BSI, of whom 39 had positive cultures at the central venous catheter insertion location. Of the 128 microorganisms isolated from the bloodstream, 53 were S. aureus, 30 were methicillin-sensitive and 23 were methicillin-resistant. Complications related to BSI included 35 cases of septicemia and 27 cases of endocarditis, of which 15 cases progressed to death. The incidence of BSI among these patients was shown to be very high, and this BSI progressed rapidly to the condition of severe infection with a high mortality rate.
本研究评估了接受血液透析（HD）的双腔中心静脉导管（CVC）患者发生血流感染（BSI）的发生率和危险因素，并鉴定了从血流中分离出的微生物。一项随访纳入了巴西圣保罗联邦大学-圣保罗大学（UNIFESP）一年内通过双腔CVC进行血液透析的所有患者（n = 156）。在该组患者中，94例发生了BSI，其中39例在中心静脉导管插入部位培养结果呈阳性。从血流中分离出的128种微生物中，53种为金黄色葡萄球菌，30种对甲氧西林敏感，23种对甲氧西林耐药。与BSI相关的并发症包括35例败血症和27例心内膜炎，其中15例进展至死亡。这些患者中BSI的发生率显示非常高，且这种BSI迅速进展为严重感染状态，死亡率很高。
