[颈动脉狭窄：治疗现状]
[Carotid artery stenosis: current state of therapy].
作者信息
Schmidt K I, Papanagiotou P, Zimmer A, Schäfers H-J, Reith W
机构信息
Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Str., 66421, Homburg/Saar, Deutschland.
出版信息
Radiologe. 2010 Jul;50(7):614-22. doi: 10.1007/s00117-009-1934-8.
Ipsilateral occlusive or embolizing carotid artery stenoses are found in 20-30% of all cases of ischemic stroke. Several randomized studies revealed endarterectomy to be the gold standard in the therapy of severe symptomatic (NASCET, ESCT) and to some extent of asymptomatic carotid stenoses (ACAS, ACST). Stent angioplasty has been established as an alternative therapeutic option although non-inferiority of this procedure has not yet been proven. We provide an overview of both procedures as well of the state of current trials.
在所有缺血性中风病例中，20%至30%可发现同侧闭塞性或栓塞性颈动脉狭窄。多项随机研究表明，内膜切除术是治疗重度症状性（北美症状性颈动脉内膜切除术试验、欧洲颈动脉外科试验）以及在一定程度上治疗无症状性颈动脉狭窄（无症状颈动脉粥样硬化研究、无症状颈动脉外科试验）的金标准。尽管尚未证实支架血管成形术的非劣效性，但它已成为一种替代治疗选择。我们将概述这两种手术以及当前试验的状况。
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