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静脉注射利多卡因在终末期严重癌性相关神经病理性疼痛中的作用。

A role for intravenous lidocaine in severe cancer-related neuropathic pain at the end-of-life.

机构信息

Ninewells Hospital and Medical School, Dundee, UK.

出版信息

Support Care Cancer. 2010 Jul;18(7):899-901. doi: 10.1007/s00520-010-0864-3. Epub 2010 Apr 29.

DOI:10.1007/s00520-010-0864-3
PMID:20429016
Abstract

BACKGROUND

Systemic administration of lidocaine has been widely reported to provide effective analgesia in both cancer and non-malignant pain.

CASE REPORT

We report the use of intravenous lidocaine in the management of cancer-related neuropathic pain and its pivotal role in restoring function and facilitating end-of-life care at home.

摘要

背景

全身性给予利多卡因已被广泛报道，在癌性和非癌性疼痛中均能提供有效的镇痛。

病例报告

我们报告了静脉内给予利多卡因治疗癌性相关神经性疼痛的应用，及其在恢复功能和促进居家临终关怀方面的关键作用。

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Support Care Cancer. 2010 Jul;18(7):899-901. doi: 10.1007/s00520-010-0864-3. Epub 2010 Apr 29.
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本文引用的文献

1
Mechanisms of analgesia of intravenous lidocaine.静脉注射利多卡因的镇痛机制。
Rev Bras Anestesiol. 2008 May-Jun;58(3):280-6. doi: 10.1590/s0034-70942008000300011.
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A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients.一项评估静脉注射利多卡因用于癌症患者阿片类药物难治性疼痛的II期试点研究。
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What is the mechanism underlying treatment of pain by systemic application of lidocaine?
癌症疼痛的报告特征：姑息治疗期刊中研究出版物的系统评价与定量分析
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Anesth Analg. 2005 Dec;101(6):1738-1749. doi: 10.1213/01.ANE.0000186348.86792.38.
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J Palliat Med. 2004 Oct;7(5):660-7. doi: 10.1089/jpm.2004.7.660.
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How to initiate and monitor infusional lidocaine for severe and/or neuropathic pain.如何启动和监测用于重度和/或神经性疼痛的静脉输注利多卡因。
J Support Oncol. 2004 Jan-Feb;2(1):90-4.
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Systemic lidocaine for neuropathic pain relief.全身性利多卡因用于缓解神经性疼痛。
Pain. 2000 Jul;87(1):7-17. doi: 10.1016/S0304-3959(00)00229-3.
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Subcutaneous lidocaine for treatment of neuropathic cancer pain.
Pain. 1991 May;45(2):145-148. doi: 10.1016/0304-3959(91)90180-6.