Misikova S, Stancak B
Eastern Slovakia Institute of Cardiac and Vascular Diseases, Kosice, Slovakia.
Bratisl Lek Listy. 2010;111(2):90-2.
To evaluate the efficacy and safety of cryoablation compared with the radiofrequency (RF) method in the treatment of typical atrial flutter (AFL).
12 patients with typical counterclockwise AFL underwent cryoablation of the cavotricuspid isthmus. Cryoablation was performed with a 9F catheter with an 8 mm tip electrode. Applications were delivered by point-by-point technique to create the ablation line. The end point of the procedure was achievement of bidirectional isthmus conduction block. Control group consisted of 12 consecutive patients who underwent the ablation by means of RF method.
We found no differences in the duration of transisthmic conduction after ablation in both groups and in the fluoroscopy time. We found significant differences in the procedural time (187 +/- 81 vs 110 +/- 35 minutes, p<0.01) and in the analgesic use (0/12 vs 12/12, p<0.01). After a 3 month follow-up all patients in both groups were free from the recurrence of AFL, 1 pacient in cryoablation group had paroxysm of atrial fibrillation.
Efficacy and safety profile of cryoablation are similiar with RF ablation. Procedural time in the cryoablation group is significantly longer but the use of analgesics can be completely avoided (Tab. 2, Ref. 20). Full Text (Free, PDF) www.bmj.sk.
评估冷冻消融术与射频（RF）消融术治疗典型心房扑动（AFL）的疗效和安全性。
12例典型逆时针方向AFL患者接受了三尖瓣峡部冷冻消融术。使用带有8mm尖端电极的9F导管进行冷冻消融。采用逐点技术进行消融以形成消融线。手术终点为实现双向峡部传导阻滞。对照组由12例连续接受RF消融术的患者组成。
我们发现两组消融后峡部传导持续时间和透视时间无差异。我们发现手术时间（187±81 vs 110±35分钟，p<0.01）和镇痛药物使用情况（0/12 vs 12/12，p<0.01）存在显著差异。3个月随访后，两组所有患者均未出现AFL复发，冷冻消融组有1例患者发生房颤发作。
冷冻消融术的疗效和安全性与RF消融术相似。冷冻消融组的手术时间明显更长，但可完全避免使用镇痛药物（表2，参考文献20）。全文（免费，PDF）www.bmj.sk。
