Kan Yingnan, Yao Ping, Xin Weihong, Chen Qianqian, Wang Jun, Yue Jian, Zhu Jiajing
Department of Otolaryngology Head and Neck, China-Japan Union Hospital of Jilin University, Changchun, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Feb;24(3):105-7.
To introduce recent progress on diagnosis and treatment of benign symmetric lipomatosis (BSL).
Detailed clinical data of 6 patients with BSL were reviewed and analyzed. We present a summary of the clinical symptoms, physical sign, diagnosis and therapeutic methods of BSL. And related literatures were discussed together.
All of 6 patients have excessive subcutaneous fat deposit predominantly around neck. One patients had upper extremity localizations. Six patients had the complication of left ventricular diastolic function changes, glucose intolerance or diabetes mellitus, chronic hepatopathy, hyperuricemia and sleep apnea syndrome in one or more. One patients with several symptoms occur simultaneously, another one female patient was accompanied by all symptoms but chronic hepatopathy. Five male patient were alcohol abusers. Total neck lipectomy and abstinence from alcohol were performed on 5 patients. One patient refused treatment. During a follow-up of 3 months to 4 years, one patients was relapsed again, and no recurrence was seen in another 4 patients. All patho logical results were nonencapsulated fat.
BSL is a lipodystrophy caused by diffuse fatty tissue, symmetry deposition in the neck and shoulder subcutaneous fascia space or deep fascial space. The highest incidence favors to middle-aged man who is alcoholic. Chronic alcohol addiction and typical clinical symptoms help to diagnosis BSL. Lipectomy represents a successful procedure in treating BSL.
介绍良性对称性脂肪瘤病（BSL）的诊断与治疗的最新进展。
回顾并分析6例BSL患者的详细临床资料。我们总结了BSL的临床症状、体征、诊断及治疗方法，并对相关文献进行了讨论。
6例患者均有以颈部周围为主的皮下脂肪过度沉积。1例患者有上肢局部病变。6例患者出现一种或多种左心室舒张功能改变、糖耐量异常或糖尿病、慢性肝病、高尿酸血症及睡眠呼吸暂停综合征等并发症。1例患者多种症状同时出现，另1例女性患者除慢性肝病外伴有所有症状。5例男性患者为酗酒者。5例患者接受了颈部脂肪切除术并戒酒。1例患者拒绝治疗。在3个月至4年的随访中，1例患者复发，另4例患者未见复发。所有病理结果均为非包膜脂肪。
BSL是一种由弥漫性脂肪组织引起的脂肪营养不良，脂肪对称沉积于颈部及肩部皮下筋膜间隙或深部筋膜间隙。发病率最高的人群为中年男性酗酒者。慢性酒精成瘾及典型的临床症状有助于诊断BSL。脂肪切除术是治疗BSL的一种成功方法。
