Department of Psychiatry, United Christian Hospital, Hong Kong 852.
Gen Hosp Psychiatry. 2010 May-Jun;32(3):284-93. doi: 10.1016/j.genhosppsych.2009.12.002. Epub 2010 Feb 20.
The aim of this study is to examine the pattern of psychiatric morbidity up to 3 months following miscarriage and to identify the risk factors of post-miscarriage depressive disorder among Chinese women in Hong Kong.
This is a longitudinal cohort study. Women were interviewed immediately after miscarriage to collect psychiatric and sociodemographic data. Three months later, 161 subjects (89%) were assessed by a 12-item General Health Questionnaire (GHQ-12) and the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) as screening and diagnostic instruments, respectively.
Three months after miscarriage, 10% of subjects suffered depressive disorder, 1.2% were diagnosed with anxiety disorder not otherwise specified, and another two subjects each suffered obsessive compulsive disorder (0.6%) and posttraumatic stress disorder (0.6%), respectively. Risk factors of post-miscarriage depression included younger age, history of infertility and past history of depression.
Given the local annual figure of more than 7000 first-trimester miscarriages, about 900 local women suffer post-miscarriage psychiatric disorder each year. This finding may prompt general hospitals in Hong Kong to screen for post-miscarriage psychiatric disorders, particularly depression.
本研究旨在探讨流产后 3 个月内精神疾病的发病模式，并确定香港女性流产后抑郁障碍的危险因素。
这是一项纵向队列研究。在流产后，立即对女性进行访谈，以收集精神疾病和社会人口学数据。3 个月后，161 名受试者（89%）分别接受了 12 项一般健康问卷（GHQ-12）和 DSM-IV 轴 I 障碍定式临床访谈（SCID）的评估，作为筛查和诊断工具。
流产后 3 个月，10%的受试者患有抑郁障碍，1.2%被诊断为未特定焦虑障碍，另有 2 名受试者分别患有强迫症（0.6%）和创伤后应激障碍（0.6%）。流产后抑郁的危险因素包括年龄较小、不孕史和既往抑郁史。
鉴于当地每年有超过 7000 例早期流产，每年约有 900 名香港女性患有流产后精神疾病。这一发现可能促使香港的综合医院对流产后精神疾病进行筛查，尤其是对抑郁障碍。
