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香港流产后精神疾病发病情况。

Psychiatric morbidity following miscarriage in Hong Kong.

机构信息

Department of Psychiatry, United Christian Hospital, Hong Kong 852.

出版信息

Gen Hosp Psychiatry. 2010 May-Jun;32(3):284-93. doi: 10.1016/j.genhosppsych.2009.12.002. Epub 2010 Feb 20.

Abstract

OBJECTIVE

The aim of this study is to examine the pattern of psychiatric morbidity up to 3 months following miscarriage and to identify the risk factors of post-miscarriage depressive disorder among Chinese women in Hong Kong.

METHOD

This is a longitudinal cohort study. Women were interviewed immediately after miscarriage to collect psychiatric and sociodemographic data. Three months later, 161 subjects (89%) were assessed by a 12-item General Health Questionnaire (GHQ-12) and the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) as screening and diagnostic instruments, respectively.

RESULTS

Three months after miscarriage, 10% of subjects suffered depressive disorder, 1.2% were diagnosed with anxiety disorder not otherwise specified, and another two subjects each suffered obsessive compulsive disorder (0.6%) and posttraumatic stress disorder (0.6%), respectively. Risk factors of post-miscarriage depression included younger age, history of infertility and past history of depression.

CONCLUSIONS

Given the local annual figure of more than 7000 first-trimester miscarriages, about 900 local women suffer post-miscarriage psychiatric disorder each year. This finding may prompt general hospitals in Hong Kong to screen for post-miscarriage psychiatric disorders, particularly depression.

摘要

目的

本研究旨在探讨流产后 3 个月内精神疾病的发病模式,并确定香港女性流产后抑郁障碍的危险因素。

方法

这是一项纵向队列研究。在流产后,立即对女性进行访谈,以收集精神疾病和社会人口学数据。3 个月后,161 名受试者(89%)分别接受了 12 项一般健康问卷(GHQ-12)和 DSM-IV 轴 I 障碍定式临床访谈(SCID)的评估,作为筛查和诊断工具。

结果

流产后 3 个月,10%的受试者患有抑郁障碍,1.2%被诊断为未特定焦虑障碍,另有 2 名受试者分别患有强迫症(0.6%)和创伤后应激障碍(0.6%)。流产后抑郁的危险因素包括年龄较小、不孕史和既往抑郁史。

结论

鉴于当地每年有超过 7000 例早期流产,每年约有 900 名香港女性患有流产后精神疾病。这一发现可能促使香港的综合医院对流产后精神疾病进行筛查,尤其是对抑郁障碍。

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